3G8I-Z-A

PDB Title ALEGLITAZAR, A NEW, POTENT, AND BALANCED PPAR ALPHA/GAMMA AGONIST FOR THE TREATMENT OF TYPE II DIABETES
Resolution (Å) 2.200
Classification TRANSCRIPTION/TRANSFERASE

Protein

Description Peroxisome proliferator-activated receptor alpha
Organism Homo sapiens
Chain A
Length 255
Binding Area (Å2) 496.17
Molecular Weight -
Aromaticity 0.09
Instability -
Isoelectric Point 6.09
Sequence DLKSLAKRIYEAYLKNFNMNKVKARVILSPPFVIHDMETLCMAEKTLVAKLKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMYX

Peptide

Description Nuclear receptor coactivator 1
Organism Homo sapiens
Chain Z
Length 8
Binding Area (Å2) 598.78
Hydrophobic (% a.a.)
50%
Molecular Weight 1055.27
Aromaticity 0.13
Instability 23.40
Isoelectric Point 8.75
Sequence HQLLRYLL

Clustering Classification

Sequence cluster S 112
Contact cluster C8
Interface cluster I8

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S112) 		Contact cluster
(C8) 		Interface cluster
(I8)
3fei-Z-A
5ji0-E-D
5two-B-A
2npa-D-C
3fur-H-A
3qt0-C-A
6fzf-C-A
2p54-B-A
6fzf-D-B
3g9e-B-A
3sp6-B-A
6fzj-C-A
3t03-C-A
6fzj-D-B
3t03-D-B
6fzp-C-A
3b1m-B-A
3h0a-E-D
3u9q-B-A
4y29-B-A
5ycn-B-A
3cs8-B-A
5dvc-B-A
5ycp-B-A
1fm6-E-D
3cwd-C-A
5dwl-B-A
1fm6-Y-X
3cwd-D-B
3kmg-B-A
3v9t-C-A
4f9m-C-A
1fm9-E-D
3kmg-E-D
3v9v-C-A
5z5s-C-A
1zgy-B-A
3v9y-B-A
5gtn-B-A
5z6s-C-A
3vn2-C-A
5gto-B-A
6ad9-B-A
1k74-E-D
2fvj-B-A
3et1-P-A
3lmp-C-A
5gtp-B-A
6d94-B-A
6izm-C-A
2gtk-B-A
3et3-P-A
6izn-C-A
2hfp-B-A
2npa-B-A
3fej-B-A
1rdt-E-D
4hee-Y-X
6k0t-D-C
6ms7-B-A
6oni-D-B
6onj-C-A
6icj-B-A
6pdz-C-B
6ijs-B-A
6pdz-D-A
6ilq-B-A
6k0t-B-A
4a1x-C-A
4pld-B-A
5q0r-B-A
5q12-B-A
5q1b-B-A
6el9-B-A
1osv-D-B
3okh-B-A
4a1x-D-B
4ple-B-A
5l11-C-A
5q0s-B-A
5q13-B-A
5q1b-D-C
5xpl-C-A
6kkb-D-X
1osv-E-B
3fxv-B-A
3oki-B-A
3ruu-B-A
4csj-B-A
4ple-H-G
5nfp-B-A
5q0s-D-C
5q13-D-C
5q1c-B-A
5y1j-U-A
2q7j-B-A
3oki-D-C
4dk7-B-A
4qe6-B-A
5nft-B-A
5q0t-B-A
5q14-B-A
5q1c-D-C
5y44-B-A
1t63-B-A
2q7l-B-A
3gn8-C-A
3olf-B-A
4dk7-D-C
4udc-B-A
5q0j-B-A
5q0u-B-A
5q14-D-C
5q1d-B-A
5y49-D-A
1yok-B-A
2qpy-B-A
3gn8-E-B
3olf-D-C
4dos-B-A
4udd-B-A
5q0j-D-C
5q0u-D-C
5q15-B-A
5q1d-D-C
5y49-E-B
6oqx-C-A
1yok-C-A
3omk-B-A
4dos-C-A
5q0k-B-A
5q0v-B-A
5q15-D-C
5q1e-B-A
6hl0-B-A
6oqy-C-A
1zdt-P-A
3k22-H-A
3omk-D-C
3up0-Q-B
4e2j-C-A
5q0l-B-A
5q0v-D-C
5q16-B-A
5q1f-B-A
6hl1-B-A
6or1-C-A
1zdt-Q-B
3k22-D-B
3omm-B-A
3up3-P-A
4e2j-E-B
5q0l-D-C
5q0w-B-A
5q16-D-C
5q1f-D-C
5yxl-B-A
1zdu-P-A
3omm-D-C
5g3j-B-A
5q0m-B-A
5q0x-B-A
5q17-B-A
5q1g-B-A
5yxl-D-C
1zdu-Q-A
3dct-B-A
3oof-B-A
5g5w-B-A
5q0n-B-A
5q0y-B-A
5q18-B-A
5q1h-B-A
1gwr-C-A
3e7c-H-A
3l0e-B-A
3oof-D-C
4p6w-B-A
5q0n-D-C
5q0y-D-C
5q18-D-C
5q1h-D-C
6itm-B-A
1gwr-D-B
2ao6-B-A
3e7c-D-B
3l3z-B-A
3ook-B-A
4p6x-B-A
5q0o-B-A
5q0z-B-A
5q19-B-A
5q1h-F-E
6itm-D-C
3ook-D-C
4a1t-C-A
4p6x-F-E
5q0o-D-C
5q0z-D-C
5q19-D-C
5q1h-H-G
1m2z-B-A
3mne-B-A
3p89-B-A
4a1t-D-B
4p6x-J-I
5ick-C-B
5q0p-B-A
5q10-B-A
5q1a-B-A
5q1i-B-A
6el6-B-A
1m2z-E-D
3mno-B-A
3plz-C-A
4a1v-C-A
4a1v-D-B
4p6x-L-K
5ick-D-A
5q0p-D-C
5q11-B-A
5q1a-D-C
5syz-C-A
6el7-B-A
1osv-C-A
3mnp-B-A
3plz-D-B