4A1V-D-B

PDB Title CO-COMPLEX STRUCTURE OF NS3-4A PROTEASE WITH THE OPTIMIZED INHIBITORY PEPTIDE CP5-46A-4D5E
Resolution (Å) 2.200
Classification HYDROLASE/PEPTIDE

Protein

Description NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3
Organism Hepacivirus C
Chain B
Length 190
Binding Area (Å2) 833.65
Molecular Weight -
Aromaticity 0.05
Instability -
Isoelectric Point 9.38
Sequence GSVVIVGRIILSGPITAYSQQTRGLLGCIITSLTGRDRNQVEGEVQVVSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWQAPPGARSLTPCSDLYLVTRHADVIPVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHAVGIFRAAVCTRGVAKAVDFVPVESMETTMRXX

Peptide

Description CP5-46A-4D5E
Organism synthetic construct
Chain D
Length 17
Binding Area (Å2) 1055.35
Hydrophobic (% a.a.)
52%
Molecular Weight 1903.05
Aromaticity 0.12
Instability 21.17
Isoelectric Point 3.84
Sequence DELVYLLDGPGYDPIHS

Clustering Classification

Sequence cluster S 112
Contact cluster C49
Interface cluster I137

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S112) 		Contact cluster
(C49) 		Interface cluster
(I137)
4a1t-C-A
4a1t-D-B
4a1v-C-A
4a1x-C-A
4a1x-D-B
3m5n-H-D
3m5o-C-A
3m5o-D-B
3rc4-B-A
3rc5-B-A
4jmy-E-A
4jmy-F-B
3g8i-Z-A
3olf-B-A
3up0-Q-B
4p6w-B-A
5nfp-B-A
5q0s-D-C
5q13-D-C
5q1c-B-A
5y44-B-A
1t63-B-A
3gn8-C-A
3olf-D-C
3up3-P-A
4p6x-B-A
5nft-B-A
5q0t-B-A
5q14-B-A
5q1c-D-C
5y49-D-A
1yok-B-A
3gn8-E-B
3omk-B-A
4p6x-F-E
5q0j-B-A
5q0u-B-A
5q14-D-C
5q1d-B-A
5y49-E-B
1yok-C-A
3k22-H-A
3omk-D-C
4p6x-J-I
5q0j-D-C
5q0u-D-C
5q15-B-A
5q1d-D-C
5yxl-B-A
1zdt-P-A
3k22-D-B
3omm-B-A
4p6x-L-K
5q0k-B-A
5q0v-B-A
5q15-D-C
5q1e-B-A
5yxl-D-C
1zdt-Q-B
3l0e-B-A
3omm-D-C
4pld-B-A
5q0l-B-A
5q0v-D-C
5q16-B-A
5q1f-B-A
6el6-B-A
1zdu-P-A
3l3z-B-A
3oof-B-A
4ple-B-A
5q0l-D-C
5q0w-B-A
5q16-D-C
5q1f-D-C
6el7-B-A
1zdu-Q-A
3oof-D-C
4csj-B-A
4ple-H-G
5q0m-B-A
5q0x-B-A
5q17-B-A
5q1g-B-A
6el9-B-A
2ao6-B-A
2q7j-B-A
3ook-B-A
4dk7-B-A
4qe6-B-A
5q0n-B-A
5q0y-B-A
5q18-B-A
5q1h-B-A
6hl0-B-A
2q7l-B-A
3ook-D-C
4dk7-D-C
4udc-B-A
5q0n-D-C
5q0y-D-C
5q18-D-C
5q1h-D-C
6hl1-B-A
1gwr-C-A
2qpy-B-A
3mne-B-A
3p89-B-A
4dos-B-A
4udd-B-A
5q0o-B-A
5q0z-B-A
5q19-B-A
5q1h-F-E
6itm-B-A
1gwr-D-B
3dct-B-A
3mno-B-A
3plz-C-A
4dos-C-A
5g3j-B-A
5q0o-D-C
5q0z-D-C
5q19-D-C
5q1h-H-G
6itm-D-C
1m2z-B-A
3e7c-H-A
3mnp-B-A
3plz-D-B
4e2j-C-A
5g5w-B-A
5q0p-B-A
5q10-B-A
5q1a-B-A
5q1i-B-A
6kkb-D-X
1m2z-E-D
3e7c-D-B
3okh-B-A
4e2j-E-B
5ick-C-B
5q0p-D-C
5q11-B-A
5q1a-D-C
5syz-C-A
6oqx-C-A
1osv-C-A
3fei-Z-A
3oki-B-A
5ick-D-A
5q0r-B-A
5q12-B-A
5q1b-B-A
5xpl-C-A
6oqy-C-A
1osv-D-B
3fxv-B-A
3oki-D-C
3ruu-B-A
5l11-C-A
5q0s-B-A
5q13-B-A
5q1b-D-C
5y1j-U-A
6or1-C-A
1osv-E-B