6HL0-B-A

PDB Title CRYSTAL STRUCTURE OF FARNESOID X RECEPTOR (FXR) WITH BOUND NCOA-2 PEPTIDE
Resolution (Å) 1.660
Classification NUCLEAR PROTEIN

Protein

Description Bile acid receptor
Organism Homo sapiens
Chain A
Length 231
Binding Area (Å2) 500.15
Molecular Weight 26995.77
Aromaticity 0.08
Instability 49.83
Isoelectric Point 5.46
Sequence SHMELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDV

Peptide

Description NCoA-2 peptide (Nuclear receptor coactivator 2), LYS-GLU-ASN-ALA-LEU-LEU-ARG-TYR-LEU-LEU-ASP-LYS-ASP
Organism Homo sapiens
Chain B
Length 13
Binding Area (Å2) 570.78
Hydrophobic (% a.a.)
38%
Molecular Weight 1590.82
Aromaticity 0.08
Instability 11.72
Isoelectric Point 6.22
Sequence KENALLRYLLDKD

Clustering Classification

Sequence cluster S 112
Contact cluster C6
Interface cluster I4

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S112) 		Contact cluster
(C6) 		Interface cluster
(I4)
3oof-B-A
5q0n-B-A
5q0y-B-A
5q18-B-A
5q1h-B-A
6hl1-B-A
3oof-D-C
5q0n-D-C
5q0y-D-C
5q18-D-C
5q1h-D-C
3ook-B-A
5q0o-B-A
5q0z-B-A
5q19-B-A
5q1h-F-E
3ook-D-C
5q0o-D-C
5q0z-D-C
5q19-D-C
5q1h-H-G
3p89-B-A
5ick-C-B
5q0p-B-A
5q10-B-A
5q1a-B-A
5q1i-B-A
5ick-D-A
5q0p-D-C
5q11-B-A
5q1a-D-C
5q0r-B-A
5q12-B-A
5q1b-B-A
5q0s-B-A
5q13-B-A
5q1b-D-C
5y1j-U-A
3dct-B-A
3oki-B-A
5q0s-D-C
5q13-D-C
5q1c-B-A
5y44-B-A
1osv-D-B
3oki-D-C
5q0t-B-A
5q14-B-A
5q1c-D-C
5y49-D-A
3olf-B-A
5q0j-B-A
5q0u-B-A
5q14-D-C
5q1d-B-A
5y49-E-B
3olf-D-C
5q0j-D-C
5q0u-D-C
5q15-B-A
5q1d-D-C
5yxl-B-A
3fxv-B-A
3omk-B-A
5q0k-B-A
5q0v-B-A
5q15-D-C
5q1e-B-A
5yxl-D-C
3omk-D-C
5q0l-B-A
5q0v-D-C
5q16-B-A
5q1f-B-A
3omm-B-A
5q0l-D-C
5q0w-B-A
5q16-D-C
5q1f-D-C
3omm-D-C
4qe6-B-A
5q0m-B-A
5q0x-B-A
5q17-B-A
3bej-E-A
3bej-F-B
6a5y-B-A
3okh-B-A
3ruu-B-A
1osv-C-A
5q1g-B-A
6itm-B-A
6itm-D-C
5q0i-B-A
6el9-B-A
1zdu-P-A
3k22-H-A
4csj-B-A
4udc-B-A
1zdu-Q-A
3k22-D-B
4dk7-B-A
4udd-B-A
2ao6-B-A
3l0e-B-A
4dk7-D-C
5g3j-B-A
2q7j-B-A
3l3z-B-A
4dos-B-A
5g5w-B-A
6kkb-D-X
1gwr-C-A
2q7l-B-A
3mne-B-A
4dos-C-A
6oqx-C-A
1gwr-D-B
2qpy-B-A
3mno-B-A
3plz-C-A
4e2j-C-A
5syz-C-A
6oqy-C-A
1m2z-B-A
3mnp-B-A
3plz-D-B
4e2j-E-B
5l11-C-A
5xpl-C-A
6or1-C-A
1m2z-E-D
4p6w-B-A
5nfp-B-A
3up0-Q-B
4p6x-B-A
5nft-B-A
3e7c-H-A
3up3-P-A
4p6x-F-E
1osv-E-B
3e7c-D-B
4a1t-C-A
4p6x-J-I
1t63-B-A
3fei-Z-A
4a1t-D-B
4p6x-L-K
1yok-B-A
4a1v-C-A
4pld-B-A
1yok-C-A
3g8i-Z-A
4a1v-D-B
4ple-B-A
6el6-B-A
1zdt-P-A
3gn8-C-A
4a1x-C-A
4ple-H-G
6el7-B-A
1zdt-Q-B
3gn8-E-B
4a1x-D-B