6PDZ-D-A

PDB Title CRYSTAL STRUCTURE OF PPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH SMRT PEPTIDE AND INVERSE AGONIST T0070907
Resolution (Å) 2.100
Classification TRANSCRIPTION

Protein

Description Peroxisome proliferator-activated receptor gamma
Organism Homo sapiens
Chain A
Length 257
Binding Area (Å2) 476.52
Molecular Weight -
Aromaticity 0.09
Instability -
Isoelectric Point 6.36
Sequence ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHIAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTLHPLLQEIYKDLYX

Peptide

Description Nuclear receptor corepressor 2
Organism Homo sapiens
Chain D
Length 12
Binding Area (Å2) 578.47
Hydrophobic (% a.a.)
75%
Molecular Weight 1345.72
Aromaticity 0.00
Instability 9.17
Isoelectric Point 8.50
Sequence MGLEAIIRKALM

Clustering Classification

Sequence cluster S 198
Contact cluster C8
Interface cluster I1764

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S198) 		Contact cluster
(C8) 		Interface cluster
(I1764)
6oni-D-B
6pdz-C-B
1fm6-Y-X
3fei-Z-A
3v9v-C-A
5ycn-B-A
1fm9-E-D
3fej-B-A
3v9y-B-A
5ycp-B-A
6izm-C-A
1k74-E-D
3fur-H-A
3vn2-C-A
5z5s-C-A
6izn-C-A
1zgy-B-A
3g8i-Z-A
4f9m-C-A
5z6s-C-A
6k0t-B-A
2fvj-B-A
3g9e-B-A
6ad9-B-A
6k0t-D-C
2gtk-B-A
3h0a-E-D
6d94-B-A
6ms7-B-A
2hfp-B-A
3kmg-B-A
4y29-B-A
6fzf-C-A
2npa-B-A
3kmg-E-D
5dvc-B-A
6fzf-D-B
6onj-C-A
2npa-D-C
3lmp-C-A
5dwl-B-A
6fzj-C-A
2p54-B-A
5gtn-B-A
6fzj-D-B
3b1m-B-A
3qt0-C-A
5gto-B-A
6fzp-C-A
3cs8-B-A
3sp6-B-A
5gtp-B-A
6icj-B-A
3cwd-C-A
3t03-C-A
5ji0-E-D
6ijs-B-A
3cwd-D-B
3t03-D-B
5two-B-A
6ilq-B-A
3et1-P-A
3u9q-B-A
1fm6-E-D
3et3-P-A
3v9t-C-A
6ivx-H-G
4mdd-C-A
4oar-B-A
3q5u-B-A
5x8q-D-C
6ivx-B-A
5x8q-H-G
6ivx-F-E