5X8Q-D-C

PDB Title CRYSTAL STRUCTURE OF THE MUTANT HUMAN ROR GAMMA LIGAND BINDING DOMAIN WITH ROCKOGENIN.
Resolution (Å) 2.200
Classification TRANSFERASE/IHIBITOR

Protein

Description Nuclear receptor ROR-gamma
Organism Homo sapiens
Chain C
Length 229
Binding Area (Å2) 652.83
Molecular Weight -
Aromaticity 0.09
Instability -
Isoelectric Point 7.19
Sequence SLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPAGKLASLCSQHVERLQIFQHLHPIVX

Peptide

Description Nuclear receptor corepressor 2
Organism Homo sapiens
Chain D
Length 14
Binding Area (Å2) 736.58
Hydrophobic (% a.a.)
71%
Molecular Weight 1516.87
Aromaticity 0.00
Instability 9.29
Isoelectric Point 8.75
Sequence NMGLEAIIRKALMG

Clustering Classification

Sequence cluster S 198
Contact cluster C155
Interface cluster I11

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S198) 		Contact cluster
(C155) 		Interface cluster
(I11)
6ivx-B-A
6ivx-F-E
6ivx-H-G
5x8q-H-G
5ni8-C-A
6g05-Q-B
3kyt-C-A
5nib-C-A
6g07-Q-B
3l0j-C-A
5ntw-Q-B
6g07-S-D
5ntw-S-D
5nu1-P-A
5nu1-Q-B
4wpf-B-A
4xt9-B-A
5x8u-B-A
5aph-C-A
5x8w-B-A
5apj-C-A
5yp6-B-A
6r7a-C-A
5g42-C-A
6e3g-C-A
6r7j-C-A
5g44-C-A
6e3g-D-B
6r7k-C-A
5g45-C-A
6esn-C-A
5g46-C-A
6fzu-P-A
5ni5-C-A
6fzu-Q-B
5ni7-C-A
6g05-P-A
3q5u-B-A
4mdd-C-A
4oar-B-A
6oni-D-B
6pdz-C-B
6pdz-D-A