5TLP-C-A

PDB Title CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH THE OBHS-BSC ANALOG, 3-FLUOROPHENYL (1R,2R,4S)-5-(4- HYDROXYPHENYL)-6-(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)-7- OXABICYCLO[2.2.1]HEPT-5-ENE-2-SULFONATE AND 3-METHYL-6-PHENYL-3H- IMIDAZO[4,5-B]PYRIDIN-2-AMINE
Resolution (Å) 2.080
Classification TRANSCRIPTION

Protein

Description Estrogen receptor
Organism Homo sapiens
Chain A
Length 235
Binding Area (Å2) 486.87
Molecular Weight -
Aromaticity 0.06
Instability -
Isoelectric Point 5.80
Sequence SLALSLTADQMVSALLDAEPPILYSEYDPPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRX

Peptide

Description NUCLEAR RECEPTOR COACTIVATOR 2
Organism Homo sapiens
Chain C
Length 10
Binding Area (Å2) 546.66
Hydrophobic (% a.a.)
40%
Molecular Weight 1272.50
Aromaticity 0.00
Instability 95.31
Isoelectric Point 8.76
Sequence HKILHRLLQD

Clustering Classification

Sequence cluster S 0
Contact cluster C1
Interface cluster I1

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S0) 		Contact cluster
(C1) 		Interface cluster
(I1)
5jmm-F-A
5kd9-C-A
5krk-C-A
4ivw-D-B
5tld-D-B
5tlv-C-A
4mg9-G-B
5tm8-C-A
4pps-C-A
5tmr-D-B
4znw-C-A
5tn4-D-B
5dk9-D-B
6cbz-C-A
5drj-D-B
5dwe-C-A
2g5o-D-B
5dxq-D-B
5dzh-D-B
2qzo-D-B
5jmm-G-B
5kd9-D-B
3uu7-F-A
5krk-D-B
4ivy-C-A
5tlf-C-A
5tlv-D-B
4mga-C-A
4pps-D-B
5tms-C-A
4znw-D-B
5tn5-C-A
5dkb-C-A
6cbz-D-B
5drm-C-A
5dwe-D-B
5dxr-C-A
2qa8-C-A
5dzi-C-A
5ehj-C-B
5kcc-C-A
5kr9-C-A
3uu7-G-B
5krl-C-A
4ivy-D-B
5tlf-D-B
5tlx-C-A
4mga-D-B
4pxm-C-A
4zn7-C-B
5tms-D-B
5tn5-D-B
5dkb-D-B
6czn-C-A
5drm-D-B
5dwg-C-A
5dxr-D-B
2qa8-D-B
5dzi-D-B
5ehj-D-A
5kcc-D-B
5kr9-D-B
3uua-F-A
5krl-D-B
4iw6-C-A
5tlg-C-A
5tlx-D-B
4mgb-C-A
4pxm-D-B
4zn7-D-A
5tmt-C-A
1gwq-C-A
5tn6-C-A
5dkg-C-A
6czn-D-B
5dtv-C-A
5dwg-D-B
5dy8-C-A
2qab-C-A
5e0w-C-A
5ei1-C-A
5kcd-C-A
5kra-C-A
3uua-G-B
5krm-C-A
4iw6-D-B
5tlg-D-B
5tly-C-A
4mgb-D-B
5tm8-D-B
4zn9-C-A
5tmt-D-B
1gwq-D-B
5tn6-D-B
5dkg-D-B
6d0f-C-A
5dtv-D-B
1zky-C-A
5dwi-C-A
5dy8-D-B
2qab-D-B
5e0w-D-B
5ei1-D-B
5kcd-D-B
5kra-D-B
3uud-C-A
5krm-D-B
4iw8-C-A
5tll-C-A
5tly-D-B
4mgc-F-A
4q13-C-A
5tm9-C-A
4zn9-D-B
5tmu-C-A
5tn7-C-A
5dl4-C-A
6d0f-D-B
5du5-C-A
1zky-D-B
5dwi-D-B
5dyb-C-A
2qgt-C-A
5e0x-C-A
5kce-C-B
5kra-G-E
3uud-D-B
5kro-C-A
4iw8-D-B
5tll-D-B
5tm1-C-A
4mgc-G-B
4q13-D-B
4znh-C-A
5tmu-D-B
5tn7-D-B
5dl4-D-B
5du5-D-B
2b1v-C-A
5dwj-C-A
5dyb-D-B
2qgt-D-B
5e0x-D-B
3erd-C-A
5kce-D-A
5kra-H-F
5kro-D-B
4iu7-C-A
4iwc-C-A
5tlm-C-A
4mg5-C-A
5tm1-D-B
4mgd-F-A
5tml-C-A
4znh-D-B
5tmv-C-A
5di7-C-A
5u2d-C-A
5dlr-C-B
5due-C-A
2b1v-D-B
5dwj-D-B
5dyd-C-A
2qgw-C-A
5e14-C-A
3l03-C-A
5kcf-C-B
5krc-C-B
4iu7-D-B
4iwc-D-B
5tlm-D-B
4mg5-D-B
5tm3-C-A
4mgd-G-B
5tml-D-B
4zns-C-A
5tmv-D-B
5di7-D-B
5u2d-D-B
5dlr-D-A
5due-D-B
2b1z-C-A
5dyd-D-B
2qgw-D-B
5e14-D-B
3l03-D-B
5kcf-D-A
5krc-D-A
4iui-C-A
4iwf-C-A
5tlo-C-A
4mg6-C-A
5tm3-D-B
5tmm-C-A
4zns-D-B
5tmw-C-A
5did-C-A
5dmc-C-A
5dug-C-A
2b1z-D-B
5dxk-C-A
5dz0-C-A
2qr9-C-A
5e15-C-A
5kct-C-A
5krf-C-A
4iui-D-B
4iwf-D-B
5tlo-D-B
4mg6-D-B
5tm4-C-A
5tmm-D-B
4znt-C-A
5tmw-D-B
1l2i-C-A
5did-D-B
5dmc-D-B
5dug-D-B
2b23-C-A
5dxk-D-B
5dz0-D-B
2qr9-D-B
5e15-D-B
5kct-D-B
5krf-D-B
4iv2-C-A
5tlp-D-B
4mg7-C-A
5tm4-D-B
4tuz-F-A
5tmo-C-A
4znt-D-B
5tmz-C-A
1l2i-D-B
5die-C-A
5dmf-C-A
5duh-C-A
2b23-D-B
5dxm-C-A
2p15-C-A
5dz1-C-A
2qse-C-A
5e19-C-B
3hm1-C-A
5kcu-C-A
3q95-C-A
5krh-C-A
4iv2-D-B
5tlt-C-A
4mg7-D-B
5tm5-C-A
4tuz-G-B
5tmo-D-B
4znu-C-A
5tmz-D-B
5die-D-B
5dmf-D-B
5duh-D-B
5dxm-D-B
2p15-D-B
5dz1-D-B
2qse-D-B
5e19-D-A
3hm1-D-B
5kcu-D-B
3q95-D-B
5krh-D-B
4dma-E-A
4iv4-C-A
5t1z-C-A
5tlt-D-B
4mg8-C-A
5tm5-D-B
4tv1-C-A
5tmq-C-A
4znu-D-B
5tn1-C-A
5dig-C-A
5dp0-C-B
1x7r-B-A
2fai-C-A
5dxp-C-A
5dz3-C-A
2qxm-C-A
5e1c-C-A
5kcw-C-A
5kri-C-A
4iv4-D-B
5t1z-D-B
5tlu-C-A
4mg8-D-B
5tm7-C-A
4pp6-C-A
4tv1-D-B
5tmq-D-B
4znv-C-B
5tn1-D-B
5dig-D-B
5dp0-D-A
5dvs-C-A
2fai-D-B
5dxp-D-B
5dz3-D-B
2qxm-D-B
5e1c-D-B
5kcw-D-B
5kri-D-B
4ivw-C-A
5tld-C-A
5tlu-D-B
4mg9-F-A
5tm7-D-B
4pp6-D-B
5tmr-C-A
4znv-D-A
5tn4-C-A
5dk9-C-A
5drj-C-A
5dvs-D-B
2g5o-C-A
5dxq-C-A
5dzh-C-A
2qzo-C-A
1gwr-C-A
1gwr-D-B
3ols-C-A
3ols-D-B
3omo-C-A
3omo-D-B
3omp-C-A
3omp-D-B
3omq-C-A
5tm9-D-B
3omq-D-B
3erd-D-B
3oll-C-A
4dma-F-B
3oll-D-B
4j26-J-B
1u9e-C-A
1yye-C-A
4zi1-B-A
1u9e-D-B
1yye-D-B
1zaf-C-A
1zaf-D-B
2j7x-B-A
2j7y-B-A
1x76-C-A
2jf9-Q-B
1x76-D-B
1x78-C-A
1x78-D-B
1x7b-C-A
2nv7-C-A
1x7b-D-B
2nv7-D-B
4j24-K-C
1x7j-C-A
4j24-I-A
1u3r-C-A
1x7j-D-B
4j24-J-B
1u3r-D-B
4j24-L-D
1u3s-C-A
4j26-I-A
1u3s-D-B
3t03-D-B
4fhh-B-A
5mj5-B-A
4xt9-B-A
1fm6-Y-X
1mzn-F-E
6jnr-D-B
2p54-B-A
5ec9-B-A
3ipu-C-A
4fhi-B-A
5mk4-B-A
4jyg-F-B
1fm9-B-A
1mzn-H-G
6r7a-C-A
2hc4-B-A
3bej-E-A
3ipu-D-B
4g1z-B-A
5mk4-D-C
4jyi-F-B
1fm9-E-D
4zsh-B-A
1n4h-B-A
1uhd-B-A
6r7j-C-A
2hfp-B-A
3bej-F-B
3kmg-B-A
4g2h-B-A
5mkj-B-A
4k4j-B-A
5a86-C-A
1nq7-B-A
1uhe-B-A
6r7k-C-A
3cwd-C-A
3kmg-E-D
4hee-Y-X
5mku-B-A
4k6i-B-A
4q0a-D-C
5a86-D-B
1nrl-C-A
1vc3-A-B
6ssq-F-B
3cwd-D-B
3kmr-C-A
4i4w-C-A
5ni5-C-A
4m8e-B-A
5aph-C-A
1nrl-D-B
6ssq-G-A
3e94-B-A
5g42-C-A
3kwy-B-A
4ia1-B-A
5ni7-C-A
4m8h-B-A
5apj-C-A
1oqp-B-A
6e3g-C-A
6sti-B-A
2k2i-B-A
5g44-C-A
3kyt-C-A
3v9y-B-A
5ni8-C-A
4rfw-G-A
1k4w-B-A
1pzl-B-A
6e3g-D-B
2npa-B-A
5g45-C-A
3ozj-B-A
3vn2-C-A
5lga-B-A
5nib-C-A
4rmd-B-A
1k74-B-A
1rdt-B-A
6esn-C-A
5dwl-B-A
2npa-D-C
3et1-P-A
5g46-C-A
3ozj-D-C
4dm6-E-A
5lmg-C-B
5nky-B-A
4oc7-B-A
4rme-B-A
1k74-E-D
5x8u-B-A
1t65-B-A
6fo8-B-1
3et3-P-A
5gtn-B-A
3l0j-C-A
3lmp-C-A
3pcu-B-A
4dm6-F-B
5lmg-D-A
5ow7-B-A
4poh-B-A
4ruj-B-A
5x8w-B-A
1tfc-C-A
6fod-B-A
3fug-B-A
5gto-B-A
5gtp-B-A
3o1d-B-A
3plx-A-B
4dm8-C-A
5lyq-B-A
5ow9-B-A
4poj-B-A
5ycn-B-A
1tfc-D-B
6icj-B-A
5hjs-C-A
3o1e-B-A
4dm8-D-B
5meo-C-A
5owd-B-A
4pp3-B-A
1mv9-B-A
5ycp-B-A
6ijs-B-A
2eeo-A-B
5hjs-D-B
3oap-B-A
5meq-C-A
4pp5-B-A
1mvc-B-A
5yp6-B-A
6ilq-B-A
5dvc-B-A
2p1t-B-A
3ipq-B-A
5ji0-E-D
3qt0-C-A
5mer-C-A
1fm6-V-U
1mzn-B-A
6a5y-B-A
6j3n-B-A
1xiu-E-A
2p1u-B-A
3ips-C-A
5ji0-F-A
3t03-C-A
4f9m-C-A
5mer-F-D
4wpf-B-A
1fm6-E-D
1mzn-D-C
6a5y-F-D
6jnr-C-A
1xiu-F-B
2p1v-B-A
5e7v-B-A
3ips-D-B