6QXK-A-B

PDB Title HUMAN PIM1 BOUND TO OX0999
Resolution (Å) 2.100
Classification TRANSFERASE

Protein

Description Serine/threonine-protein kinase pim-1
Organism Homo sapiens
Chain B
Length 270
Binding Area (Å2) 504.72
Molecular Weight -
Aromaticity 0.10
Instability -
Isoelectric Point 5.20
Sequence ESQYQVGPLLGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHX

Peptide

Description Pimtide
Organism synthetic construct
Chain A
Length 8
Binding Area (Å2) 712.73
Hydrophobic (% a.a.)
12%
Molecular Weight 1092.26
Aromaticity 0.00
Instability 237.25
Isoelectric Point 12.48
Sequence RKRRRHPS

Clustering Classification

Sequence cluster S 217
Contact cluster C17
Interface cluster I17