5UUM-D-B

PDB Title HUMAN MCL-1 IN COMPLEX WITH A BFL-1-SPECIFIC SELECTED PEPTIDE
Resolution (Å) 2.350
Classification APOPTOSIS

Protein

Description Induced myeloid leukemia cell differentiation protein Mcl-1
Organism Homo sapiens
Chain B
Length 160
Binding Area (Å2) 884.45
Molecular Weight -
Aromaticity 0.08
Instability -
Isoelectric Point 8.07
Sequence GSDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEXXXX

Peptide

Description Bfl-1 specific peptide FS2
Organism synthetic construct
Chain D
Length 23
Binding Area (Å2) 1026.36
Hydrophobic (% a.a.)
47%
Molecular Weight 2623.88
Aromaticity 0.04
Instability 40.56
Isoelectric Point 6.22
Sequence QWVREIAAGLRRAADDVNAQVER

Clustering Classification

Sequence cluster S 35
Contact cluster C53
Interface cluster I55

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S35) 		Contact cluster
(C53) 		Interface cluster
(I55)
5c6h-B-A
2rod-B-A
5uum-C-A
2jm6-A-B
2roc-B-A
3d7v-B-A
3kz0-C-A
3kz0-D-B
6mbe-B-A
2kbw-B-A
6qfi-B-A
5fmk-B-A
2v6q-B-A
5twa-D-A
2vog-B-A
5twa-C-B
2voh-B-A
5tzp-B-A
2wh6-B-A
5tzq-C-B
2xpx-B-A
5tzq-D-A
5ua5-B-A
3i1h-B-A
3io8-D-C
5uuk-B-A
1bxl-B-A
5vmo-B-A
1g5j-B-A
3mqp-B-A
6fbx-B-A
2jby-B-A
4bd6-C-A
6mbc-B-A
4uf1-B-A
4zif-B-A
2m04-B-A
4zih-B-A
6qg8-B-A