6QG8-B-A

PDB Title STRUCTURE OF HUMAN BCL-2 IN COMPLEX WITH PUMA BH3 PEPTIDE
Resolution (Å) 1.900
Classification APOPTOSIS

Protein

Description Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Bcl-2-like protein 1
Organism Homo sapiens
Chain A
Length 137
Binding Area (Å2) 729.44
Molecular Weight 15889.55
Aromaticity 0.15
Instability 33.86
Isoelectric Point 4.67
Sequence DNREIVMKYISYKLSQRGYEWDESEVVHQTLRQAGDDFSLRYRRDFAEMSSQLHLTPGTAYASFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSVLVDNIAAWMATYLNDHLHTWIQDNGGWDAFVELYG

Peptide

Description Bcl-2-binding component 3
Organism Homo sapiens
Chain B
Length 20
Binding Area (Å2) 856.16
Hydrophobic (% a.a.)
40%
Molecular Weight 2416.63
Aromaticity 0.05
Instability 89.80
Isoelectric Point 4.36
Sequence EEEQWAREIGAQLRRMADDL

Clustering Classification

Sequence cluster S 35
Contact cluster C13
Interface cluster I12

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S35) 		Contact cluster
(C13) 		Interface cluster
(I12)
3io8-D-C
5fmk-B-A
1bxl-B-A
1g5j-B-A
1pq1-B-A
5vau-F-B
2bzw-B-A
3fdl-B-A
5b1z-C-A
5vau-H-D
5b1z-D-B
5vax-E-A
3io8-B-A
5vax-F-B
5fcg-C-A
5vax-G-C
2p1l-B-A
5fmj-B-A
5vax-H-D
2p1l-D-C
3r85-E-A
5vay-F-B
2p1l-F-E
3r85-F-B
5vay-H-D
2p1l-H-G
3r85-G-C
2pon-A-B
3r85-H-D
6dcn-D-A
6dcn-C-B
4qvf-B-A
6dco-C-A
6dco-D-B
4z9v-C-A
4z9v-D-B
2xpx-B-A
4zih-B-A
2jby-B-A
3i1h-B-A
2jm6-A-B
5c6h-B-A
2m04-B-A
3mqp-B-A
5twa-D-A
5twa-C-B
5vmo-B-A
5tzp-B-A
2roc-B-A
4bd6-C-A
5tzq-C-B
2rod-B-A
5tzq-D-A
2v6q-B-A
4uf1-B-A
5ua5-B-A
2vog-B-A
5uuk-B-A
6fbx-B-A
2voh-B-A
5uum-C-A
6mbc-B-A
2wh6-B-A
4zif-B-A
5uum-D-B