3MQP-B-A

PDB Title CRYSTAL STRUCTURE OF HUMAN BFL-1 IN COMPLEX WITH NOXA BH3 PEPTIDE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR2930
Resolution (Å) 2.240
Classification APOPTOSIS

Protein

Description Bcl-2-related protein A1
Organism Homo sapiens
Chain A
Length 150
Binding Area (Å2) 887.82
Molecular Weight 17237.50
Aromaticity 0.12
Instability 20.95
Isoelectric Point 5.26
Sequence TDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPK

Peptide

Description Phorbol-12-myristate-13-acetate-induced protein 1
Organism Homo sapiens
Chain B
Length 25
Binding Area (Å2) 1079.07
Hydrophobic (% a.a.)
44%
Molecular Weight 2978.43
Aromaticity 0.08
Instability 46.28
Isoelectric Point 8.24
Sequence AELEVECATQLRRFGDKLNFRQKLL

Clustering Classification

Sequence cluster S 35
Contact cluster C75
Interface cluster I84