2ROC-B-A

PDB Title SOLUTION STRUCTURE OF MCL-1 COMPLEXED WITH PUMA
Resolution (Å)
Classification APOPTOSIS

Protein

Description Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
Organism Mus musculus
Chain A
Length 162
Binding Area (Å2) 924.31
Molecular Weight 18232.43
Aromaticity 0.09
Instability 34.62
Isoelectric Point 8.20
Sequence GPLGSEDDLYRQSLEIISRYLREQATGSKDSKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEGDVKSFSRVMVHVFKDGVTNWGRIVTLISFGAFVAKHLKSVNQESFIEPLAETITDVLVRTKRDWLVKQRGWDGFVEFFHVQDLEGG

Peptide

Description Bcl-2-binding component 3
Organism Mus musculus
Chain B
Length 27
Binding Area (Å2) 1048.22
Hydrophobic (% a.a.)
37%
Molecular Weight 3319.62
Aromaticity 0.07
Instability 67.47
Isoelectric Point 4.77
Sequence EEEWAREIGAQLRRIADDLNAQYERRM

Clustering Classification

Sequence cluster S 35
Contact cluster C53
Interface cluster I55

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S35) 		Contact cluster
(C53) 		Interface cluster
(I55)
2jm6-A-B
2rod-B-A
5c6h-B-A
5uum-C-A
5uum-D-B
2kbw-B-A
6mbe-B-A
6qfi-B-A
3d7v-B-A
3kz0-C-A
3kz0-D-B
4uf1-B-A
6mbc-B-A
4zif-B-A
2m04-B-A
4zih-B-A
6qg8-B-A
2v6q-B-A
5fmk-B-A
2vog-B-A
5twa-D-A
2voh-B-A
5twa-C-B
2wh6-B-A
5tzp-B-A
2xpx-B-A
5tzq-C-B
5tzq-D-A
3i1h-B-A
5ua5-B-A
3io8-D-C
5uuk-B-A
1bxl-B-A
1g5j-B-A
3mqp-B-A
5vmo-B-A
2jby-B-A
4bd6-C-A
6fbx-B-A