2ROC-B-A

PDB Title SOLUTION STRUCTURE OF MCL-1 COMPLEXED WITH PUMA
Resolution (Å)
Classification APOPTOSIS

Protein

Description Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
Organism Mus musculus
Chain A
Length 162
Binding Area (Å2) 924.31
Molecular Weight 18232.43
Aromaticity 0.09
Instability 34.62
Isoelectric Point 8.20
Sequence GPLGSEDDLYRQSLEIISRYLREQATGSKDSKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEGDVKSFSRVMVHVFKDGVTNWGRIVTLISFGAFVAKHLKSVNQESFIEPLAETITDVLVRTKRDWLVKQRGWDGFVEFFHVQDLEGG

Peptide

Description Bcl-2-binding component 3
Organism Mus musculus
Chain B
Length 27
Binding Area (Å2) 1048.22
Hydrophobic (% a.a.)
37%
Molecular Weight 3319.62
Aromaticity 0.07
Instability 67.47
Isoelectric Point 4.77
Sequence EEEWAREIGAQLRRIADDLNAQYERRM

Clustering Classification

Sequence cluster S 35
Contact cluster C53
Interface cluster I55