2KBW-B-A

PDB Title SOLUTION STRUCTURE OF HUMAN MCL-1 COMPLEXED WITH HUMAN BID_BH3 PEPTIDE
Resolution (Å)
Classification APOPTOSIS

Protein

Description Induced myeloid leukemia cell differentiation protein Mcl-1
Organism Homo sapiens
Chain A
Length 160
Binding Area (Å2) 994.63
Molecular Weight 18295.48
Aromaticity 0.08
Instability 42.92
Isoelectric Point 5.87
Sequence AEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEG

Peptide

Description BH3-interacting domain death agonist
Organism Homo sapiens
Chain B
Length 31
Binding Area (Å2) 1120.58
Hydrophobic (% a.a.)
48%
Molecular Weight 3404.76
Aromaticity 0.00
Instability 83.18
Isoelectric Point 4.83
Sequence SESQEDIIRNIARHLAQVGDSMDRSIPPGLV

Clustering Classification

Sequence cluster S 31
Contact cluster C53
Interface cluster I55

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S31) 		Contact cluster
(C53) 		Interface cluster
(I55)
6qfi-B-A
2jm6-A-B
2roc-B-A
2rod-B-A
3d7v-B-A
3kz0-C-A
3kz0-D-B
5c6h-B-A
5uum-C-A
5uum-D-B
6mbe-B-A
1zy3-B-A
2voi-B-A
4bd2-C-A
4zeq-B-A
4zig-B-A
4zii-C-A