2M04-B-A

PDB Title SOLUTION STRUCTURE OF BCL-XL IN COMPLEX WITH PUMA BH3 PEPTIDE
Resolution (Å)
Classification APOPTOSIS/PROTEIN BINDING

Protein

Description Bcl-2-like protein 1
Organism Homo sapiens
Chain A
Length 174
Binding Area (Å2) 1365.87
Molecular Weight 19826.68
Aromaticity 0.12
Instability 41.68
Isoelectric Point 4.64
Sequence MSAMSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERLE

Peptide

Description Bcl-2-binding component 3
Organism Homo sapiens
Chain B
Length 25
Binding Area (Å2) 1576.66
Hydrophobic (% a.a.)
36%
Molecular Weight 3049.29
Aromaticity 0.08
Instability 54.76
Isoelectric Point 4.66
Sequence EEQWAREIGAQLRRMADDLNAQYER

Clustering Classification

Sequence cluster S 35
Contact cluster C944
Interface cluster I870

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S35) 		Contact cluster
(C944) 		Interface cluster
(I870)
2xpx-B-A
5uuk-B-A
3i1h-B-A
5uum-C-A
3io8-D-C
5uum-D-B
3mqp-B-A
5vmo-B-A
4bd6-C-A
6fbx-B-A
4uf1-B-A
6mbc-B-A
1bxl-B-A
4zif-B-A
6qg8-B-A
1g5j-B-A
4zih-B-A
2jby-B-A
5c6h-B-A
2jm6-A-B
5fmk-B-A
2roc-B-A
5twa-D-A
2rod-B-A
5twa-C-B
2v6q-B-A
5tzp-B-A
2vog-B-A
5tzq-C-B
2voh-B-A
5tzq-D-A
2wh6-B-A
5ua5-B-A