6MBC-B-A

PDB Title HUMAN BFL-1 IN COMPLEX WITH THE DESIGNED PEPTIDE DF4
Resolution (Å) 1.750
Classification APOPTOSIS

Protein

Description Bcl-2-related protein A1
Organism Homo sapiens
Chain A
Length 152
Binding Area (Å2) 1056.62
Molecular Weight 17425.75
Aromaticity 0.12
Instability 20.61
Isoelectric Point 5.27
Sequence GMTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPK

Peptide

Description dF4
Organism synthetic construct
Chain B
Length 23
Binding Area (Å2) 1230.95
Hydrophobic (% a.a.)
39%
Molecular Weight 2783.25
Aromaticity 0.09
Instability 41.71
Isoelectric Point 8.07
Sequence SLLEKLAEYLRQMADEINKKYVK

Clustering Classification

Sequence cluster S 35
Contact cluster C75
Interface cluster I84