2HGT-J-H

PDB Title STRUCTURE OF THE HIRUGEN AND HIRULOG 1 COMPLEXES OF ALPHA-THROMBIN
Resolution (Å) 2.200
Classification HYDROLASE/HYDROLASE INHIBITOR

Protein

Description ALPHA-THROMBIN (LARGE SUBUNIT)
Organism Homo sapiens
Chain H
Length 253
Binding Area (Å2) 336.76
Molecular Weight 29167.22
Aromaticity 0.11
Instability 33.30
Isoelectric Point 8.76
Sequence IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE

Peptide

Description Hirulog
Organism Hirudo medicinalis
Chain J
Length 6
Binding Area (Å2) 411.92
Hydrophobic (% a.a.)
50%
Molecular Weight 748.78
Aromaticity 0.17
Instability 77.40
Isoelectric Point 3.57
Sequence DFEEIP

Clustering Classification

Sequence cluster S 79
Contact cluster C822
Interface cluster I14

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S79) 		Contact cluster
(C822) 		Interface cluster
(I14)
1hxf-I-H
1lhc-I-H
3ldx-I-H
1lhd-I-H
1lhe-I-H
1lhf-I-H
3vxe-J-H
1lhg-I-H
4ax9-I-H
4ud9-I-H
5afy-I-H
1tmt-J-H
5gim-D-B
1vzq-I-H
1a3b-I-H
1w7g-I-H
1a3e-I-H
1eb1-A-H
2r2m-H-B
1fph-I-H
1g37-B-A
3c27-H-B
1hxe-I-H
3hki-F-E
3p6z-C-B
3p6z-I-H
1nrr-R-H
1thr-I-H
2pux-C-B
3hki-C-B
3b23-C-B