6MBE-B-A

PDB Title HUMAN MCL-1 IN COMPLEX WITH THE DESIGNED PEPTIDE DM7
Resolution (Å) 2.250
Classification APOPTOSIS

Protein

Description Induced myeloid leukemia cell differentiation protein Mcl-1
Organism Homo sapiens
Chain A
Length 155
Binding Area (Å2) 865.36
Molecular Weight -
Aromaticity 0.08
Instability -
Isoelectric Point 8.78
Sequence GSDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDX

Peptide

Description dM7
Organism synthetic construct
Chain B
Length 22
Binding Area (Å2) 993.21
Hydrophobic (% a.a.)
45%
Molecular Weight 2582.98
Aromaticity 0.00
Instability 35.19
Isoelectric Point 4.49
Sequence DKTLEEIARELLKLALEIDKEI

Clustering Classification

Sequence cluster S 1799
Contact cluster C60
Interface cluster I55

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S1799) 		Contact cluster
(C60) 		Interface cluster
(I55)
2kbw-B-A
2roc-B-A
2rod-B-A
3d7v-B-A
3kz0-C-A
3kz0-D-B
5c6h-B-A
5uum-C-A
5uum-D-B
6qfi-B-A
2jm6-A-B