3D7V-B-A

PDB Title CRYSTAL STRUCTURE OF MCL-1 IN COMPLEX WITH AN MCL-1 SELECTIVE BH3 LIGAND
Resolution (Å) 2.030
Classification APOPTOSIS

Protein

Description Induced myeloid leukemia cell differentiation protein Mcl-1
Organism Homo sapiens
Chain A
Length 148
Binding Area (Å2) 912.98
Molecular Weight -
Aromaticity 0.08
Instability -
Isoelectric Point 8.10
Sequence DDLYRQSLEIISRYLREQATGSKDGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEXXXX

Peptide

Description Bcl-2-like protein 11
Organism Homo sapiens
Chain B
Length 23
Binding Area (Å2) 1053.67
Hydrophobic (% a.a.)
43%
Molecular Weight 2749.00
Aromaticity 0.13
Instability 82.81
Isoelectric Point 6.26
Sequence RPEIWIAQEARRIGDEANAYYAR

Clustering Classification

Sequence cluster S 165
Contact cluster C60
Interface cluster I55

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S165) 		Contact cluster
(C60) 		Interface cluster
(I55)
6qfi-B-A
3kz0-C-A
3kz0-D-B
2roc-B-A
2rod-B-A
6mbe-B-A
5c6h-B-A
2jm6-A-B
5uum-C-A
5uum-D-B
2kbw-B-A
5wos-B-A
2vm6-B-A
3fdl-B-A
3io8-B-A
4b4s-B-A
4d2m-B-A
4d2m-D-C
4qvf-B-A
4zie-C-A
1pq1-B-A
2k7w-B-A
5vwv-B-A