2XUM-S-A

PDB Title FACTOR INHIBITING HIF (FIH) Q239H MUTANT IN COMPLEX WITH ZN(II), NOG AND ASP-SUBSTRATE PEPTIDE (20-MER)
Resolution (Å) 2.200
Classification OXIDOREDUCTASE/PEPTIDE

Protein

Description HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR
Organism Homo sapiens
Chain A
Length 351
Binding Area (Å2) 903.53
Molecular Weight -
Aromaticity 0.12
Instability -
Isoelectric Point 5.47
Sequence MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRHSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYNXX

Peptide

Description ASP-SUBSTRATE PEPTIDE 2
Organism synthetic construct
Chain S
Length 18
Binding Area (Å2) 1150.37
Hydrophobic (% a.a.)
50%
Molecular Weight 1979.19
Aromaticity 0.00
Instability -18.62
Isoelectric Point 4.43
Sequence EVVKLLLEHGADVDAQDK

Clustering Classification

Sequence cluster S 173
Contact cluster C39
Interface cluster I79

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S173) 		Contact cluster
(C39) 		Interface cluster
(I79)
4b7k-B-A
2y0i-S-A
4b7e-B-A
3p3n-B-A
5jwp-B-A
1h2k-S-A
1h2l-S-A
3d8c-B-A
2ilm-S-A
6h9j-D-A
6ha6-D-A
6hc8-E-A
6hkp-S-A
6hl5-S-A
6hl6-S-A
1h2m-S-A
1x76-C-A
2gtk-B-A
3h0a-E-D
5two-B-A
6gev-B-A
1x76-D-B
3l3x-B-A
4qjr-B-A
5unj-C-A
6gg8-B-A
1x78-C-A
2nv7-C-A
4uda-B-A
5z5s-C-A
6ggg-B-A
1x78-D-B
2nv7-D-B
3sp6-B-A
4udb-B-A
5z6s-C-A
1x7b-C-A
3u9q-B-A
4y29-B-A
6ad9-B-A
1x7b-D-B
3b1m-B-A
3v9t-C-A
6fzf-C-A
1x7j-C-A
3bqd-B-A
3v9v-C-A
5l7e-B-A
6fzf-D-B
1x7j-D-B
3cs8-B-A
3zrk-X-A
5l7g-B-A
6fzj-C-A
1yye-C-A
3zrk-Y-B
5l7h-B-A
6fzj-D-B
1yye-D-B
3f7d-B-A
3zrl-X-A
5mwp-B-A
6fzp-C-A
6izm-C-A
1u3r-C-A
1zaf-C-A
3fej-B-A
3zrl-Y-B
5mwy-B-A
6fzu-P-A
6izn-C-A
1u3r-D-B
1zaf-D-B
3fur-H-A
3zrm-X-A
5ntw-Q-B
6fzu-Q-B
6k0t-B-A
1u3s-C-A
1zgy-B-A
3g9e-B-A
3zrm-Y-B
5ntw-S-D
6g05-P-A
6k0t-D-C
1u3s-D-B
2a3i-B-A
3gyt-B-A
4afj-X-A
5nu1-P-A
6g05-Q-B
6ms7-B-A
1u9e-C-A
2a4j-B-A
3gyu-B-A
4afj-Y-B
5nu1-Q-B
6g07-Q-B
6nwk-B-A
1u9e-D-B
2fvj-B-A
3h0a-B-A
5q0i-B-A
6g07-S-D
6nwl-B-A