1H2K-S-A

PDB Title FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH HIF-1 ALPHA FRAGMENT PEPTIDE
Resolution (Å) 2.150
Classification TRANSCRIPTION ACTIVATOR/INHIBITOR

Protein

Description FACTOR INHIBITING HIF1
Organism Homo sapiens
Chain A
Length 334
Binding Area (Å2) 1265.84
Molecular Weight -
Aromaticity 0.13
Instability -
Isoelectric Point 5.30
Sequence EPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYNXX

Peptide

Description HYPOXIA-INDUCIBLE FACTOR 1 ALPHA
Organism Homo sapiens
Chain S
Length 24
Binding Area (Å2) 1456.01
Hydrophobic (% a.a.)
50%
Molecular Weight 2676.00
Aromaticity 0.04
Instability 67.55
Isoelectric Point 4.02
Sequence LTSYDCEVNAPILLQGEELLRALD

Clustering Classification

Sequence cluster S 34
Contact cluster C39
Interface cluster I79

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S34) 		Contact cluster
(C39) 		Interface cluster
(I79)
3d8c-B-A
5jwp-B-A
1h2l-S-A
2xum-S-A
2y0i-S-A
3p3n-B-A
4b7e-B-A
4b7k-B-A
1h2m-S-A
2ilm-S-A
6h9j-D-A
6ha6-D-A
6hc8-E-A
6hkp-S-A
6hl5-S-A
6hl6-S-A
1l3e-A-B