4ERY-D-A

PDB Title X-RAY STRUCTURE OF WDR5-MLL3 WIN MOTIF PEPTIDE BINARY COMPLEX
Resolution (Å) 1.300
Classification TRANSCRIPTION/TRANSFERASE

Protein

Description WD repeat-containing protein 5
Organism Homo sapiens
Chain A
Length 304
Binding Area (Å2) 543.06
Molecular Weight 33448.65
Aromaticity 0.10
Instability 25.16
Isoelectric Point 8.56
Sequence VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC

Peptide

Description Histone-lysine N-methyltransferase MLL3
Organism Homo sapiens
Chain D
Length 14
Binding Area (Å2) 754.62
Hydrophobic (% a.a.)
42%
Molecular Weight 1476.68
Aromaticity 0.00
Instability 114.74
Isoelectric Point 8.19
Sequence VNPTGCARSEPKMS

Clustering Classification

Sequence cluster S 135
Contact cluster C19
Interface cluster I18

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S135) 		Contact cluster
(C19) 		Interface cluster
(I18)
4erq-D-A
3eg6-C-A
4erq-E-B
3emh-B-A
4erz-D-C
3p4f-C-A
4erz-E-A
4erz-F-B
3uvk-B-A
4es0-C-A
3uvl-B-A
4esg-C-B
3uvm-B-A
4esg-D-A
3uvn-B-A
4ewr-C-A
3uvn-D-C
3uvo-B-A
2co0-D-C
4cy3-D-A
2h9m-B-A
4cy5-D-A
3psl-C-A
4o45-B-A
4cy1-C-B
4cy1-D-A
2co0-B-A
4cy2-D-A
2l8j-B-A
6f4r-B-A
6f4s-B-A