3EMH-B-A

PDB Title STRUCTURAL BASIS OF WDR5-MLL INTERACTION
Resolution (Å) 1.370
Classification GENE REGULATION

Protein

Description WD repeat-containing protein 5
Organism Homo sapiens
Chain A
Length 300
Binding Area (Å2) 402.32
Molecular Weight 33003.11
Aromaticity 0.10
Instability 25.71
Isoelectric Point 8.63
Sequence PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS

Peptide

Description Mixed-lineage leukemia protein 1
Organism Homo sapiens
Chain B
Length 6
Binding Area (Å2) 604.19
Hydrophobic (% a.a.)
50%
Molecular Weight 681.74
Aromaticity 0.00
Instability 8.33
Isoelectric Point 6.79
Sequence ARAEVH

Clustering Classification

Sequence cluster S 135
Contact cluster C19
Interface cluster I18

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S135) 		Contact cluster
(C19) 		Interface cluster
(I18)
4erq-D-A
4erq-E-B
3eg6-C-A
4ery-D-A
3p4f-C-A
4erz-D-C
4erz-E-A
3uvk-B-A
4erz-F-B
3uvl-B-A
4es0-C-A
3uvm-B-A
4esg-C-B
3uvn-B-A
4esg-D-A
3uvn-D-C
4ewr-C-A
3uvo-B-A
2h9m-B-A
3psl-C-A
4o45-B-A
4cy1-C-B
4cy1-D-A
4cy2-D-A
2co0-B-A
4cy3-D-A
2co0-D-C
4cy5-D-A
2l8j-B-A
6f4r-B-A
6f4s-B-A