3UVM-B-A

PDB Title CRYSTAL STRUCTURE OF WDR5 IN COMPLEX WITH THE WDR5-INTERACTING MOTIF OF MLL4
Resolution (Å) 1.570
Classification TRANSCRIPTION

Protein

Description WD repeat-containing protein 5
Organism Homo sapiens
Chain A
Length 304
Binding Area (Å2) 578.99
Molecular Weight 33448.65
Aromaticity 0.10
Instability 25.16
Isoelectric Point 8.56
Sequence VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC

Peptide

Description Histone-lysine N-methyltransferase MLL4
Organism Homo sapiens
Chain B
Length 10
Binding Area (Å2) 861.81
Hydrophobic (% a.a.)
60%
Molecular Weight 1105.25
Aromaticity 0.10
Instability 12.23
Isoelectric Point 8.75
Sequence GAARAEVYLR

Clustering Classification

Sequence cluster S 135
Contact cluster C19
Interface cluster I18

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S135) 		Contact cluster
(C19) 		Interface cluster
(I18)
4erq-D-A
4erq-E-B
3eg6-C-A
4ery-D-A
3emh-B-A
4erz-D-C
3p4f-C-A
4erz-E-A
4erz-F-B
3uvk-B-A
4es0-C-A
3uvl-B-A
4esg-C-B
3uvn-B-A
4esg-D-A
3uvn-D-C
4ewr-C-A
3uvo-B-A
2h9m-B-A
3psl-C-A
4o45-B-A
4cy1-C-B
4cy1-D-A
4cy2-D-A
2co0-B-A
4cy3-D-A
2co0-D-C
4cy5-D-A
2l8j-B-A
6f4r-B-A
6f4s-B-A