3UVL-B-A

PDB Title CRYSTAL STRUCTURE OF WDR5 IN COMPLEX WITH THE WDR5-INTERACTING MOTIF OF MLL3
Resolution (Å) 2.200
Classification TRANSCRIPTION

Protein

Description WD repeat-containing protein 5
Organism Homo sapiens
Chain A
Length 303
Binding Area (Å2) 470.17
Molecular Weight 33333.56
Aromaticity 0.10
Instability 25.21
Isoelectric Point 8.68
Sequence VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC

Peptide

Description Histone-lysine N-methyltransferase MLL3
Organism Homo sapiens
Chain B
Length 9
Binding Area (Å2) 708.49
Hydrophobic (% a.a.)
55%
Molecular Weight 946.08
Aromaticity 0.00
Instability 66.51
Isoelectric Point 8.75
Sequence GSARAEPKM

Clustering Classification

Sequence cluster S 135
Contact cluster C19
Interface cluster I18

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S135) 		Contact cluster
(C19) 		Interface cluster
(I18)
3uvo-B-A
4erq-D-A
4erq-E-B
3eg6-C-A
4ery-D-A
3emh-B-A
4erz-D-C
3p4f-C-A
4erz-E-A
4erz-F-B
3uvk-B-A
4es0-C-A
3uvm-B-A
4esg-C-B
3uvn-B-A
4esg-D-A
3uvn-D-C
4ewr-C-A
4o45-B-A
4cy1-C-B
4cy1-D-A
4cy2-D-A
2co0-B-A
4cy3-D-A
2co0-D-C
4cy5-D-A
2h9m-B-A
3psl-C-A
6f4r-B-A
6f4s-B-A
2l8j-B-A