3LNZ-L-K

PDB Title CRYSTAL STRUCTURE OF HUMAN MDM2 WITH A 12-MER PEPTIDE INHIBITOR PMI (N8A MUTANT)
Resolution (Å) 1.950
Classification LIGASE/LIGASE INHIBITOR

Protein

Description E3 ubiquitin-protein ligase Mdm2
Organism Homo sapiens
Chain K
Length 84
Binding Area (Å2) 525.36
Molecular Weight -
Aromaticity 0.12
Instability -
Isoelectric Point 9.55
Sequence TLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVX

Peptide

Description 12-mer peptide inhibitor
Organism -
Chain L
Length 12
Binding Area (Å2) 655.70
Hydrophobic (% a.a.)
50%
Molecular Weight 1384.53
Aromaticity 0.25
Instability 24.62
Isoelectric Point 4.00
Sequence TSFAEYWALLSP

Clustering Classification

Sequence cluster S 155
Contact cluster C46
Interface cluster I31

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S155) 		Contact cluster
(C46) 		Interface cluster
(I31)
3eqy-D-B
3lnz-J-I
3eqs-B-A
1t4f-P-M
1ycq-B-A
3jzo-P-A
3jzp-P-A
3jzq-P-A
3jzq-Q-B
3jzr-P-A
3jzs-P-A
3dab-B-A
3dab-D-C
3dab-H-G
2mps-B-A
2mwy-B-A
2jdo-C-A
2jdr-C-A
2uw9-C-A
2x39-C-A
3cqu-C-A
3mv5-C-A
3cqw-C-A
3mvh-B-A
3qkk-C-A
3qkl-C-A
3e87-D-B
1o6k-C-A
3e88-D-B
1o6l-C-A