3JZS-P-A

PDB Title HUMAN MDM2 LIGANDED WITH A 12MER PEPTIDE INHIBITOR (PDIQ)
Resolution (Å) 1.780
Classification LIGASE

Protein

Description E3 ubiquitin-protein ligase Mdm2
Organism Homo sapiens
Chain A
Length 83
Binding Area (Å2) 534.17
Molecular Weight 9801.52
Aromaticity 0.12
Instability 22.12
Isoelectric Point 9.55
Sequence TLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLV

Peptide

Description pDIQ peptide (12mer)
Organism -
Chain P
Length 12
Binding Area (Å2) 645.26
Hydrophobic (% a.a.)
25%
Molecular Weight 1562.68
Aromaticity 0.25
Instability 26.82
Isoelectric Point 4.51
Sequence ETFEHWWSQLLS

Clustering Classification

Sequence cluster S 166
Contact cluster C46
Interface cluster I31

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S166) 		Contact cluster
(C46) 		Interface cluster
(I31)
3jzp-P-A
3jzq-P-A
3jzq-Q-B
3jzr-P-A
3jzo-P-A
3lnz-J-I
3lnz-L-K
1t4f-P-M
1ycq-B-A
3dab-B-A
3dab-D-C
3dab-H-G
3eqs-B-A
3eqy-D-B
2mps-B-A
2mwy-B-A
1sqk-B-A
3sjh-B-A
3u8x-B-A
3u8x-D-C
3u9d-B-A
3u9d-D-C
3u9z-C-A
6ijq-A-B
6t2e-B-A