1T4F-P-M

PDB Title STRUCTURE OF HUMAN MDM2 IN COMPLEX WITH AN OPTIMIZED P53 PEPTIDE
Resolution (Å) 1.900
Classification LIGASE

Protein

Description Ubiquitin-protein ligase E3 Mdm2
Organism Homo sapiens
Chain M
Length 88
Binding Area (Å2) 462.88
Molecular Weight 10386.14
Aromaticity 0.11
Instability 25.81
Isoelectric Point 9.24
Sequence EQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVV

Peptide

Description optimized p53 peptide
Organism -
Chain P
Length 9
Binding Area (Å2) 594.84
Hydrophobic (% a.a.)
44%
Molecular Weight 1216.36
Aromaticity 0.33
Instability -2.63
Isoelectric Point 4.37
Sequence RFMDYWEGL

Clustering Classification

Sequence cluster S 915
Contact cluster C46
Interface cluster I31

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S915) 		Contact cluster
(C46) 		Interface cluster
(I31)
3jzr-P-A
3jzs-P-A
3lnz-J-I
3lnz-L-K
1ycq-B-A
3dab-B-A
3dab-D-C
3dab-H-G
3eqs-B-A
3eqy-D-B
3jzo-P-A
3jzp-P-A
3jzq-P-A
3jzq-Q-B
2mps-B-A
2mwy-B-A