2Q7K-B-A

PDB Title THE ANDROGEN RECEPTOR PROSTATE CANCER MUTANT H874Y LIGAND BINDING DOMAIN BOUND WITH TESTOSTERONE AND AN AR 20-30 PEPTIDE
Resolution (Å) 1.800
Classification HORMONE

Protein

Description Androgen receptor
Organism Homo sapiens
Chain A
Length 243
Binding Area (Å2) 463.31
Molecular Weight -
Aromaticity 0.12
Instability -
Isoelectric Point 8.46
Sequence PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIASCSRRFYQLTKLLDSVQPIARELYQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQX

Peptide

Description Androgen receptor
Organism Homo sapiens
Chain B
Length 10
Binding Area (Å2) 550.89
Hydrophobic (% a.a.)
60%
Molecular Weight 1110.22
Aromaticity 0.20
Instability 44.45
Isoelectric Point 5.52
Sequence GAFQNLFQSV

Clustering Classification

Sequence cluster S 223
Contact cluster C7
Interface cluster I5

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S223) 		Contact cluster
(C7) 		Interface cluster
(I5)
5cj6-B-A
1xow-B-A
4oh5-B-A
4ok1-B-A
3v49-B-A
2q7i-B-A
3v4a-B-A
4oey-B-A
4ofu-B-A
6el9-B-A
3k22-D-B
3l3x-B-A
5g3j-B-A
6gev-B-A
2a3i-B-A
3l3z-B-A
4oha-B-A
5g5w-B-A
6gg8-B-A
2ao6-B-A
3mne-B-A
5jjm-G-A
6ggg-B-A
2ovh-B-A
3mno-B-A
4okt-B-A
1m2z-B-A
2pkl-B-A
3mnp-B-A
4okw-B-A
5jjm-I-C
1m2z-E-D
2q3y-B-A
4okx-B-A
5jjm-J-D
1t5z-B-A
4p6w-B-A
5l7e-B-A
1t63-B-A
2q7j-B-A
4csj-B-A
4p6x-B-A
5l7g-B-A
1t65-B-A
2q7l-B-A
4e2j-C-A
4p6x-F-E
5l7h-B-A
1t73-B-A
2qpy-B-A
4e2j-E-B
4p6x-J-I
5mwp-B-A
1t74-B-A
3bqd-B-A
4p6x-L-K
5mwy-B-A
1t76-B-A
3e7c-H-A
4oar-B-A
4uda-B-A
5nfp-B-A
1t79-B-A
3e7c-D-B
4udb-B-A
5nft-B-A
1t7f-B-A
3gn8-C-A
4oez-B-A
4udc-B-A
6el6-B-A
1t7m-B-A
3gn8-E-B
4ofr-B-A
4udd-B-A
6el7-B-A
1t7r-B-A
3k22-H-A
5jjm-H-B
6nwk-B-A
6nwl-B-A
4lsj-B-A