2KWF-B-A

PDB Title THE STRUCTURE OF E-PROTEIN ACTIVATION DOMAIN 1 BOUND TO THE KIX DOMAIN OF CBP/P300 ELUCIDATES LEUKEMIA INDUCTION BY E2A-PBX1
Resolution (Å)
Classification TRANSCRIPTION

Protein

Description CREB-binding protein
Organism Homo sapiens
Chain A
Length 87
Binding Area (Å2) 668.33
Molecular Weight 10331.68
Aromaticity 0.08
Instability 60.12
Isoelectric Point 9.22
Sequence GVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRL

Peptide

Description Transcription factor 4
Organism Homo sapiens
Chain B
Length 19
Binding Area (Å2) 768.64
Hydrophobic (% a.a.)
47%
Molecular Weight 2020.17
Aromaticity 0.11
Instability -3.43
Isoelectric Point 3.84
Sequence GSGTDKELSDLLDFSAMFS

Clustering Classification

Sequence cluster S 122
Contact cluster C869
Interface cluster I257

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S122) 		Contact cluster
(C869) 		Interface cluster
(I257)
2lxs-B-A
2lxt-B-A
1rdt-E-D
2knh-B-A
2mh0-A-B