6TJM-B-A

PDB Title CRYSTAL STRUCTURE OF AN ESTROGEN RECEPTOR ALPHA 8-MER PHOSPHOPEPTIDE IN COMPLEX WITH 14-3-3SIGMA STABILIZED BY PYRROLIDONE1
Resolution (Å) 1.850
Classification SIGNALING PROTEIN

Protein

Description 14-3-3 protein sigma
Organism Homo sapiens
Chain A
Length 231
Binding Area (Å2) 325.02
Molecular Weight -
Aromaticity 0.07
Instability -
Isoelectric Point 4.97
Sequence GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTXX

Peptide

Description C-terminal phosphopeptide of human estrogen receptor alpha
Organism Homo sapiens
Chain B
Length 4
Binding Area (Å2) 445.70
Hydrophobic (% a.a.)
100%
Molecular Weight 432.51
Aromaticity 0.25
Instability 103.80
Isoelectric Point 5.52
Sequence FPAV

Clustering Classification

Sequence cluster S 215
Contact cluster C11
Interface cluster I1840