6HKF-B-A

PDB Title TERNARY COMPLEX OF ESTROGEN RECEPTOR ALPHA PEPTIDE AND 14-3-3 SIGMA C42 MUTANT BOUND TO DISULFIDE FRAGMENT PPI STABILIZER 4
Resolution (Å) 1.800
Classification PROTEIN BINDING

Protein

Description 14-3-3 protein sigma
Organism Homo sapiens
Chain A
Length 240
Binding Area (Å2) 305.23
Molecular Weight -
Aromaticity 0.07
Instability -
Isoelectric Point 4.85
Sequence GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSNEERCLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTXXXX

Peptide

Description Estrogen receptor
Organism Homo sapiens
Chain B
Length 4
Binding Area (Å2) 404.98
Hydrophobic (% a.a.)
100%
Molecular Weight 432.51
Aromaticity 0.25
Instability 103.80
Isoelectric Point 5.52
Sequence FPAV

Clustering Classification

Sequence cluster S 215
Contact cluster C11
Interface cluster I33

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S215) 		Contact cluster
(C11) 		Interface cluster
(I33)
5n10-F-B
6hhp-B-A
4jc3-B-A
6hkb-B-A
4jdd-B-A
6hmt-B-A
6hmu-B-A
4qli-B-A
1o9d-P-A
2v7d-P-A
2v7d-Q-B
2v7d-R-C
2v7d-S-D
3e6y-C-A
3e6y-D-B
6tjm-B-A
6tl3-B-A
6qdr-B-A
5ewz-C-A
6qds-B-A
5exa-C-B
6qdt-B-A
2o02-P-A
5exa-D-A
6qzr-R-F
2o02-Q-B
5f74-B-A
6qzr-J-E
5mhc-P-A
6qzr-M-B
5mxo-P-A
6qzr-N-A
6qzr-O-C
5xy9-C-A
6qzr-T-G
5xy9-D-B
6qzr-U-H
6bcy-C-A
3lw1-P-A
6bcy-G-E
4gnt-B-A
4n7g-B-A