5EWZ-C-A

PDB Title SMALL-MOLECULE STABILIZATION OF THE 14-3-3/GAB2 PPI INTERFACE
Resolution (Å) 2.340
Classification SIGNALING PROTEIN

Protein

Description 14-3-3 protein zeta/delta
Organism Homo sapiens
Chain A
Length 230
Binding Area (Å2) 548.13
Molecular Weight -
Aromaticity 0.08
Instability -
Isoelectric Point 5.00
Sequence DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSX

Peptide

Description GRB2-associated-binding protein 2
Organism Homo sapiens
Chain C
Length 8
Binding Area (Å2) 675.02
Hydrophobic (% a.a.)
62%
Molecular Weight 954.15
Aromaticity 0.00
Instability 134.50
Isoelectric Point 12.00
Sequence PRRNLPAM

Clustering Classification

Sequence cluster S 725
Contact cluster C11
Interface cluster I101

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S725) 		Contact cluster
(C11) 		Interface cluster
(I101)
5exa-C-B
5exa-D-A
6bcy-C-A
6bcy-G-E
5mhc-P-A
5xy9-C-A
5xy9-D-B
6qzr-U-H
3e6y-C-A
6tjm-B-A
3e6y-D-B
6hhp-B-A
6tl3-B-A
3lw1-P-A
6hkb-B-A
4gnt-B-A
6hkf-B-A
4jc3-B-A
6hmt-B-A
4jdd-B-A
6hmu-B-A
4n7g-B-A
6qdr-B-A
4qli-B-A
6qds-B-A
6qdt-B-A
1o9d-P-A
5f74-B-A
6qzr-R-F
2o02-P-A
6qzr-J-E
2o02-Q-B
5mxo-P-A
6qzr-M-B
2v7d-P-A
5n10-F-B
6qzr-N-A
2v7d-Q-B
6qzr-O-C
2v7d-R-C
6qzr-T-G
2v7d-S-D