5U5T-C-A

PDB Title CRYSTAL STRUCTURE OF EED IN COMPLEX WITH H3K27ME3 PEPTIDE AND 3- (BENZO[D][1,3]DIOXOL-4-YLMETHYL)PIPERIDINE-1-CARBOXIMIDAMIDE
Resolution (Å) 1.600
Classification TRANSCRIPTION/TRANSFERASE

Protein

Description Polycomb protein EED
Organism Homo sapiens
Chain A
Length 349
Binding Area (Å2) 1168.00
Molecular Weight -
Aromaticity 0.11
Instability -
Isoelectric Point 6.16
Sequence KYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVECTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLX

Peptide

Description Histone-lysine N-methyltransferase EZH2
Organism Homo sapiens
Chain C
Length 26
Binding Area (Å2) 1335.58
Hydrophobic (% a.a.)
26%
Molecular Weight 3250.67
Aromaticity 0.04
Instability 95.46
Isoelectric Point 10.83
Sequence SSNRQKILERTEILNQEWKQRRIQPV

Clustering Classification

Sequence cluster S 175
Contact cluster C85
Interface cluster I95

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S175) 		Contact cluster
(C85) 		Interface cluster
(I95)
5gsa-C-A
5h17-B-A
5h19-B-A
5u5t-D-B
5u62-C-A
5wuk-B-A
2qxv-B-A
3cc5-C-A
3cc5-F-D
3ch1-C-A
3ch1-F-D
3ch1-I-G
3ch1-L-J