2QXV-B-A

PDB Title STRUCTURAL BASIS OF EZH2 RECOGNITION BY EED
Resolution (Å) 1.820
Classification GENE REGULATION

Protein

Description Embryonic ectoderm development
Organism Mus musculus
Chain A
Length 352
Binding Area (Å2) 1368.78
Molecular Weight 40536.72
Aromaticity 0.11
Instability 36.19
Isoelectric Point 6.20
Sequence FKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL

Peptide

Description Enhancer of zeste homolog 2
Organism Mus musculus
Chain B
Length 29
Binding Area (Å2) 1620.27
Hydrophobic (% a.a.)
27%
Molecular Weight 3618.09
Aromaticity 0.07
Instability 73.34
Isoelectric Point 10.83
Sequence TMFSSNRQKILERTETLNQEWKQRRIQPV

Clustering Classification

Sequence cluster S 175
Contact cluster C85
Interface cluster I95

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S175) 		Contact cluster
(C85) 		Interface cluster
(I95)
5gsa-C-A
5h17-B-A
5h19-B-A
5u5t-C-A
5u5t-D-B
5u62-C-A
5wuk-B-A
3ch1-C-A
3ch1-F-D
3ch1-I-G
3ch1-L-J
3cc5-C-A
3cc5-F-D