1HUC-A-B

PDB Title THE REFINED 2.15 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF HUMAN LIVER CATHEPSIN B: THE STRUCTURAL BASIS FOR ITS SPECIFICITY
Resolution (Å) 2.100
Classification THIOL PROTEASE

Protein

Description CATHEPSIN B
Organism Homo sapiens
Chain B
Length 205
Binding Area (Å2) 2096.36
Molecular Weight 22415.70
Aromaticity 0.12
Instability 22.72
Isoelectric Point 5.19
Sequence VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTD

Peptide

Description CATHEPSIN B
Organism Homo sapiens
Chain A
Length 47
Binding Area (Å2) 2466.66
Hydrophobic (% a.a.)
42%
Molecular Weight 5208.80
Aromaticity 0.09
Instability 43.71
Isoelectric Point 4.95
Sequence LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTN

Clustering Classification

Sequence cluster S 80
Contact cluster C162
Interface cluster I179

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S80) 		Contact cluster
(C162) 		Interface cluster
(I179)
1csb-D-E
1huc-C-D
1sp4-A-B
5grg-C-A