1CSB-D-E

PDB Title CRYSTAL STRUCTURE OF CATHEPSIN B INHIBITED WITH CA030 AT 2.1 ANGSTROMS RESOLUTION: A BASIS FOR THE DESIGN OF SPECIFIC EPOXYSUCCINYL INHIBITORS
Resolution (Å) 2.000
Classification HYDROLASE/HYDROLASE INHIBITOR

Protein

Description CATHEPSIN B heavy chain
Organism Homo sapiens
Chain E
Length 206
Binding Area (Å2) 2100.51
Molecular Weight -
Aromaticity 0.12
Instability -
Isoelectric Point 5.17
Sequence VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDX

Peptide

Description CATHEPSIN B light chain
Organism Homo sapiens
Chain D
Length 47
Binding Area (Å2) 2452.44
Hydrophobic (% a.a.)
42%
Molecular Weight 5208.80
Aromaticity 0.09
Instability 43.71
Isoelectric Point 4.95
Sequence LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTN

Clustering Classification

Sequence cluster S 80
Contact cluster C162
Interface cluster I179

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S80) 		Contact cluster
(C162) 		Interface cluster
(I179)
1huc-A-B
1huc-C-D
1sp4-A-B
5grg-C-A