5EHC-B-A

PDB Title CO-CRYSTAL STRUCTURE OF EIF4E WITH NUCLEOTIDE MIMETIC INHIBITOR.
Resolution (Å) 2.400
Classification TRANSLATION

Protein

Description Eukaryotic translation initiation factor 4E
Organism Homo sapiens
Chain A
Length 187
Binding Area (Å2) 664.63
Molecular Weight -
Aromaticity 0.12
Instability -
Isoelectric Point 7.19
Sequence EVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATTKNRFVVX

Peptide

Description Eukaryotic translation initiation factor 4 gamma 1
Organism Homo sapiens
Chain B
Length 14
Binding Area (Å2) 678.21
Hydrophobic (% a.a.)
42%
Molecular Weight 1847.12
Aromaticity 0.29
Instability 33.33
Isoelectric Point 9.70
Sequence KKRYDREFLLGFQF

Clustering Classification

Sequence cluster S 219
Contact cluster C22
Interface cluster I30

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S219) 		Contact cluster
(C22) 		Interface cluster
(I30)
2w97-E-A
2w97-F-B
1ejh-E-A
1ejh-F-B
5ei3-B-A
1ejh-G-C
1ejh-H-D
2v8w-B-A
2v8x-B-A
2v8y-B-A
3am7-B-A
3m94-C-A
3u7x-C-A
3u7x-D-B
1ej4-B-A
1wkw-B-A
5me5-B-A
5xln-B-A
4ue9-B-A
4ued-B-A
5aby-B-A
5nvn-D-C
5t48-B-A
2jgc-B-A