1WKW-B-A

PDB Title CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF EIF4E-M7GPPPA-4EBP1 PEPTIDE
Resolution (Å) 2.100
Classification TRANSLATION/PROTEIN BINDING

Protein

Description Eukaryotic translation initiation factor 4E
Organism Homo sapiens
Chain A
Length 192
Binding Area (Å2) 675.74
Molecular Weight -
Aromaticity 0.11
Instability -
Isoelectric Point 7.90
Sequence EVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVVX

Peptide

Description Eukaryotic translation initiation factor 4E binding protein 1
Organism Homo sapiens
Chain B
Length 20
Binding Area (Å2) 709.85
Hydrophobic (% a.a.)
45%
Molecular Weight 2353.72
Aromaticity 0.10
Instability 69.61
Isoelectric Point 9.37
Sequence PGGTRIIYDRKFLMECRNSP

Clustering Classification

Sequence cluster S 432
Contact cluster C22
Interface cluster I30

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S432) 		Contact cluster
(C22) 		Interface cluster
(I30)
3am7-B-A
1ejh-H-D
2v8w-B-A
2v8x-B-A
2v8y-B-A
2w97-E-A
2w97-F-B
3m94-C-A
3u7x-C-A
3u7x-D-B
1ej4-B-A
1ejh-E-A
1ejh-F-B
5ehc-B-A
1ejh-G-C
5ei3-B-A
5me5-B-A
2jgc-B-A
5nvn-D-C
5t48-B-A
5xln-B-A
4ue9-B-A
4ued-B-A
5aby-B-A