3P8O-D-B

PDB Title CRYSTAL STRUCTURE OF HCV NS3/NS4A PROTEASE COMPLEXED WITH DES-BROMINE ANALOGUE OF BI 201335
Resolution (Å) 2.300
Classification HYDROLASE/HYDROLASE INHIBITOR

Protein

Description HCV serine protease NS3
Organism Hepacivirus C
Chain B
Length 184
Binding Area (Å2) 1045.82
Molecular Weight -
Aromaticity 0.05
Instability -
Isoelectric Point 9.10
Sequence APITAYSQQTRGLLGCIITSLTGRDKNQVDGEVQVLSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWPAPPGARSMTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHVVGIFRAAVCTRGVAKAVDFIPVESMETTMRASXX

Peptide

Description HCV non-structural protein 4A
Organism Hepacivirus C
Chain D
Length 13
Binding Area (Å2) 1430.79
Hydrophobic (% a.a.)
69%
Molecular Weight 1340.65
Aromaticity 0.00
Instability 4.45
Isoelectric Point 11.00
Sequence KGSVVIVGRIILS

Clustering Classification

Sequence cluster S 13
Contact cluster C13
Interface cluster I20

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S13) 		Contact cluster
(C13) 		Interface cluster
(I20)
1w3c-C-A
1w3c-D-B
3kee-F-B
4ktc-B-A
3kee-G-C
4ktc-D-C
3kee-H-D
1dxp-C-A
4i31-C-A
1dxp-D-B
4i31-D-B
1dy8-C-A
4i32-C-A
1dy8-D-B
4i32-D-B
1dy9-C-A
4i33-C-A
1dy9-D-B
3p8n-C-A
4i33-D-B
3p8n-D-B
3p8o-C-A
4jmy-C-A
4jmy-D-B
3rc5-B-A
4jmy-E-A
4a1t-C-A
4jmy-F-B
4a1t-D-B
4a1v-C-A
4a1v-D-B
4a1x-C-A
4a1x-D-B
3m5m-C-B
3m5n-F-B
3m5n-H-D
3m5o-C-A
3m5o-D-B
3rc4-B-A
1awu-B-A
1awv-G-A
1awv-H-B
1awv-I-C
1awv-J-D
1awv-K-E
3lly-B-A
1awv-L-F
3llz-B-A
1awq-B-A
1awr-G-A
1awr-H-B
1awr-I-C
1awr-J-D
1jot-B-A
4iim-E-B
1awr-K-E
1pxd-B-A
1awr-L-F
1ugx-B-A