3M5N-H-D

PDB Title CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH N-TERMINAL PRODUCT 4B5A
Resolution (Å) 1.900
Classification HYDROLASE/HYDROLASE INHIBITOR

Protein

Description NS3/4A
Organism Hepacivirus C
Chain D
Length 199
Binding Area (Å2) 373.61
Molecular Weight -
Aromaticity 0.05
Instability -
Isoelectric Point 9.33
Sequence HMASMKKKGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSAGGPLLCPAGHAVGIFRAAVSTRGVAKAVDFIPVESLETTMX

Peptide

Description SECTTPC peptide
Organism Hepacivirus C
Chain H
Length 7
Binding Area (Å2) 482.01
Hydrophobic (% a.a.)
14%
Molecular Weight 739.82
Aromaticity 0.00
Instability 134.66
Isoelectric Point 4.00
Sequence SECTTPC

Clustering Classification

Sequence cluster S 576
Contact cluster C13
Interface cluster I86