3M5M-C-B

PDB Title AVOIDING DRUG RESISTANCE AGAINST HCV NS3/4A PROTEASE INHIBITORS
Resolution (Å) 1.700
Classification HYDROLASE/HYDROLASE INHIBITOR

Protein

Description NS3/4A
Organism Hepacivirus C
Chain B
Length 198
Binding Area (Å2) 450.10
Molecular Weight -
Aromaticity 0.05
Instability -
Isoelectric Point 9.32
Sequence MASMKKKGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSAGGPLLCPAGHAVGIFRAAVSTRGVAKAVDFIPVESLETTMX

Peptide

Description FDEMEEC Peptide
Organism Hepacivirus C
Chain C
Length 7
Binding Area (Å2) 601.67
Hydrophobic (% a.a.)
28%
Molecular Weight 901.96
Aromaticity 0.14
Instability 135.54
Isoelectric Point 3.50
Sequence FDEMEEC

Clustering Classification

Sequence cluster S 148
Contact cluster C13
Interface cluster I86

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S148) 		Contact cluster
(C13) 		Interface cluster
(I86)
3m5n-F-B
3m5n-H-D
3m5o-C-A
3m5o-D-B
3rc4-B-A
3rc5-B-A
4jmy-E-A
4jmy-F-B
3kee-H-D
4a1x-C-A
4ktc-B-A
1dxp-C-A
4a1x-D-B
4ktc-D-C
1dxp-D-B
1dy8-C-A
1dy8-D-B
1dy9-C-A
1dy9-D-B
3p8n-C-A
4i31-C-A
3p8n-D-B
4i31-D-B
1w3c-C-A
3p8o-C-A
4i32-C-A
1w3c-D-B
3p8o-D-B
4i32-D-B
4i33-C-A
4i33-D-B
4a1t-C-A
4jmy-C-A
4a1t-D-B
4jmy-D-B
3kee-F-B
4a1v-C-A
3kee-G-C
4a1v-D-B
3lca-Q-A
4aif-D-A
5mgx-A-F
4aif-E-B
5mgx-B-G
4cgq-Q-A
5mgx-C-E
4cgu-C-A
5mgx-D-H
5njx-B-A
1elr-B-A
6fdp-B-A
6hpg-a-A
6hpg-c-C
2bug-B-A
6hpg-d-D
2l6j-B-A
6hpg-e-E
2lsv-B-A
3fp2-Q-A