2AK5-D-B

PDB Title BETA PIX-SH3 COMPLEXED WITH A CBL-B PEPTIDE
Resolution (Å) 1.850
Classification ENDOCYTOSIS/EXOCYTOSIS

Protein

Description Rho guanine nucleotide exchange factor 7
Organism Rattus norvegicus
Chain B
Length 64
Binding Area (Å2) 365.40
Molecular Weight 7281.85
Aromaticity 0.13
Instability 32.56
Isoelectric Point 6.08
Sequence GSANSQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYVREIKPS

Peptide

Description 8-residue peptide from a signal transduction protein CBL-B
Organism Homo sapiens
Chain D
Length 8
Binding Area (Å2) 435.43
Hydrophobic (% a.a.)
50%
Molecular Weight 1003.21
Aromaticity 0.00
Instability 52.70
Isoelectric Point 12.30
Sequence RPPKPRPR

Clustering Classification

Sequence cluster S 195
Contact cluster C1422
Interface cluster I730