5UWI-D-C

PDB Title CRYSTAL STRUCTURE OF HDAC5 NES PEPTIDE IN COMPLEX WITH CRM1-RAN-RANBP1
Resolution (Å) 2.140
Classification PROTEIN TRANSPORT

Protein

Description Exportin-1
Organism Saccharomyces cerevisiae
Chain C
Length 1001
Binding Area (Å2) 792.31
Molecular Weight 114749.15
Aromaticity 0.09
Instability 41.16
Isoelectric Point 5.45
Sequence GSMEGILDFSNDLDIALLDQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTNPQSKFIALSILDKLITRKWKLLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPQNWPEFIPELIGSSSSSVNVCENNMIVLKLLSEEVFDFSAEQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQGSSSSLIVATLESLLRYLHWIPYRYIYETNILELLSTKFMTSPDTRAITLKCLTEVSNLKIPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKATYANANGNDQSFLQDLAMFLTTYLARNRALLESDESLRELLLNAHQYLIQLSKIEERELFKTTLDYWHNLVADLFYEPLKKHIYEEICSQLRLVIIENMVRPEKESDTIQLYKSEREVLVYLTHLNVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSEDTEKRFVVTVIKDLLGLCEQKRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDTFIKIVQKCKYHFVIQQPRESEPFIQTIIRDIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLMQLPNMAWDTIVEQSTANPTLLLDSETVKIIANIIKTNVAVCTSMGADFYPQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYISKARNLDDVVKVLVEPLLNAVLEDYMNNVPDARDAEVLNCMTTVVEKVGHMIPQGVILILQSVFECTLDMINKDFTEYPEHRVEFYKLLKVINEKSFAAFLELPPAAFKLFVDAICWAFKHNNRDVEVNGLQIALDLVKNIERMGNVPFANEFHKNYFFIFVSETFFVLTDSDHKSGFSKQALLLMKLISLVYDNKISVPLYQEAEVPQGTSNQVYLSQYLANMLSNAFPHLTSEQIASFLSALTKQCKDLVVFKGTLRDFLVQIKEVGGDPTDYLFAE

Peptide

Description Histone deacetylase 5
Organism Homo sapiens
Chain D
Length 16
Binding Area (Å2) 901.44
Hydrophobic (% a.a.)
56%
Molecular Weight 1627.81
Aromaticity 0.06
Instability 7.07
Isoelectric Point 3.79
Sequence SYEAETVSAMALLSVG

Clustering Classification

Sequence cluster S 1644
Contact cluster C31
Interface cluster I28

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S1644) 		Contact cluster
(C31) 		Interface cluster
(I28)
5uwp-D-C
5uwq-D-C
5uwr-D-C
5uws-D-C
5uwt-D-C
5uwu-D-C
5uww-D-C
5xoj-D-C
2l1l-A-B
6a3a-D-C
6a3c-D-C
5dhf-D-C
6cit-D-C
5di9-D-C
5dif-D-C
5uwh-D-C
5uwj-D-C
5uwo-D-C
3wyg-D-C