5U5T-D-B

PDB Title CRYSTAL STRUCTURE OF EED IN COMPLEX WITH H3K27ME3 PEPTIDE AND 3- (BENZO[D][1,3]DIOXOL-4-YLMETHYL)PIPERIDINE-1-CARBOXIMIDAMIDE
Resolution (Å) 1.600
Classification TRANSCRIPTION/TRANSFERASE

Protein

Description Polycomb protein EED
Organism Homo sapiens
Chain B
Length 351
Binding Area (Å2) 1251.22
Molecular Weight -
Aromaticity 0.11
Instability -
Isoelectric Point 6.16
Sequence YSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLXXX

Peptide

Description Histone-lysine N-methyltransferase EZH2
Organism Homo sapiens
Chain D
Length 28
Binding Area (Å2) 1451.74
Hydrophobic (% a.a.)
32%
Molecular Weight 3529.04
Aromaticity 0.07
Instability 89.36
Isoelectric Point 10.83
Sequence MFSSNRQKILERTEILNQEWKQRRIQPV

Clustering Classification

Sequence cluster S 175
Contact cluster C92
Interface cluster I95

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S175) 		Contact cluster
(C92) 		Interface cluster
(I95)
5gsa-C-A
5h17-B-A
5h19-B-A
5u5t-C-A
5u62-C-A
5wuk-B-A
2qxv-B-A
3ch1-L-J
3cc5-C-A
3cc5-F-D
3ch1-C-A
3ch1-F-D
3ch1-I-G