4ZEQ-B-A

PDB Title CRYSTAL STRUCTURE OF HUMAN BFL-1 IN COMPLEX WITH TBID BH3 PEPTIDE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HX9247
Resolution (Å) 1.800
Classification APOPTOSIS

Protein

Description Bcl-2-related protein A1
Organism Homo sapiens
Chain A
Length 149
Binding Area (Å2) 886.28
Molecular Weight 17136.40
Aromaticity 0.12
Instability 21.02
Isoelectric Point 5.27
Sequence DCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPK

Peptide

Description BH3-interacting domain death agonist
Organism Homo sapiens
Chain B
Length 26
Binding Area (Å2) 1047.28
Hydrophobic (% a.a.)
50%
Molecular Weight 2889.21
Aromaticity 0.00
Instability 75.03
Isoelectric Point 5.43
Sequence QEDIIRNIARHLAQVGDSMDRSIPPG

Clustering Classification

Sequence cluster S 31
Contact cluster C84
Interface cluster I84

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S31) 		Contact cluster
(C84) 		Interface cluster
(I84)
2voi-B-A
5uuk-B-A
6mbc-B-A
2vm6-B-A
2vog-B-A
2voh-B-A
3i1h-B-A
3mqp-B-A
4zig-B-A
4zii-C-A
1zy3-B-A
2kbw-B-A
4bd2-C-A