3CWW-D-B

PDB Title CRYSTAL STRUCTURE OF IDE-BRADYKININ COMPLEX
Resolution (Å) 1.960
Classification HYDROLASE

Protein

Description Insulin-degrading enzyme
Organism Homo sapiens
Chain B
Length 957
Binding Area (Å2) 183.59
Molecular Weight -
Aromaticity 0.11
Instability -
Isoelectric Point 6.10
Sequence NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKAGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDAVIAKWQNAALNGKFKLPTKNEFIPTNFEILPLEAAATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEARFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALADVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLAAYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKADIIKFYKEMLAVDAPRRHKVSVHVLAREMLSQAPALPQPEVIQNMTAFKRGLPLFPLVKPHXXXX

Peptide

Description bradykinin N-terminal tetrapeptide analogue
Organism -
Chain D
Length 4
Binding Area (Å2) 288.20
Hydrophobic (% a.a.)
100%
Molecular Weight 354.40
Aromaticity 0.00
Instability 151.95
Isoelectric Point 5.57
Sequence APPA

Clustering Classification

Sequence cluster S 673
Contact cluster C112
Interface cluster I169

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S673) 		Contact cluster
(C112) 		Interface cluster
(I169)
3cww-E-A
3e50-C-A
4pes-C-A
4pes-D-B
3ofi-C-A
3ofi-D-B
2i3h-C-A
2i3h-D-B
4c2c-C-A
4c2g-C-A