3AM7-B-A

PDB Title CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF EIF4E-M7GTP-4EBP2 PEPTIDE
Resolution (Å) 2.200
Classification TRANSLATION/PROTEIN BINDING

Protein

Description Eukaryotic translation initiation factor 4E
Organism Homo sapiens
Chain A
Length 191
Binding Area (Å2) 726.48
Molecular Weight -
Aromaticity 0.12
Instability -
Isoelectric Point 7.90
Sequence EVANPEHYIKHPLQNRWALWFFKNDKSKTWQANRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVVX

Peptide

Description Eukaryotic translation initiation factor 4E-binding protein 2
Organism Homo sapiens
Chain B
Length 19
Binding Area (Å2) 780.23
Hydrophobic (% a.a.)
42%
Molecular Weight 2277.58
Aromaticity 0.11
Instability 52.67
Isoelectric Point 10.84
Sequence PGGTRIIYDRKFLLDRRNS

Clustering Classification

Sequence cluster S 432
Contact cluster C22
Interface cluster I30

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S432) 		Contact cluster
(C22) 		Interface cluster
(I30)
1wkw-B-A
2v8w-B-A
2v8x-B-A
2v8y-B-A
2w97-E-A
2w97-F-B
3m94-C-A
3u7x-C-A
3u7x-D-B
1ej4-B-A
1ejh-E-A
1ejh-F-B
5ehc-B-A
1ejh-G-C
5ei3-B-A
1ejh-H-D
2jgc-B-A
5t48-B-A
5xln-B-A
4ue9-B-A
4ued-B-A
5aby-B-A
5me5-B-A
5nvn-D-C