3BZI-E-A

PDB Title MOLECULAR AND STRUCTURAL BASIS OF POLO-LIKE KINASE 1 SUBSTRATE RECOGNITION: IMPLICATIONS IN CENTROSOMAL LOCALIZATION
Resolution (Å) 2.100
Classification TRANSFERASE

Protein

Description Serine/threonine-protein kinase PLK1
Organism Homo sapiens
Chain A
Length 223
Binding Area (Å2) 375.81
Molecular Weight 25780.15
Aromaticity 0.10
Instability 40.22
Isoelectric Point 6.66
Sequence DCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS

Peptide

Description 9 mer peptide from M-phase inducer phosphatase 3
Organism Homo sapiens
Chain E
Length 6
Binding Area (Å2) 482.60
Hydrophobic (% a.a.)
50%
Molecular Weight 645.77
Aromaticity 0.00
Instability 81.57
Isoelectric Point 5.52
Sequence LLCSPN

Clustering Classification

Sequence cluster S 1205
Contact cluster C82
Interface cluster I66

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S1205) 		Contact cluster
(C82) 		Interface cluster
(I66)
1q4k-F-C
1umw-F-B
3p37-F-C
4o56-B-A
5dms-B-A
5j19-D-A
1q4k-E-B
3c5l-B-A
3hik-B-A
5dmv-D-C