2PVF-B-A

PDB Title CRYSTAL STRUCTURE OF TYROSINE PHOSPHORYLATED ACTIVATED FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN IN COMPLEX WITH ATP ANALOG AND SUBSTRATE PEPTIDE
Resolution (Å) 1.800
Classification TRANSFERASE

Protein

Description Fibroblast growth factor receptor 2
Organism Homo sapiens
Chain A
Length 291
Binding Area (Å2) 268.21
Molecular Weight -
Aromaticity 0.08
Instability -
Isoelectric Point 6.04
Sequence ELPEDPKWEFPRDKLTLGKPLGEGAFGQVVMAEAVGIDKDKPVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEXSYQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDXXKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTXXX

Peptide

Description Fibroblast growth factor receptor 2
Organism Homo sapiens
Chain B
Length 4
Binding Area (Å2) 353.65
Hydrophobic (% a.a.)
25%
Molecular Weight 552.57
Aromaticity 0.25
Instability 89.00
Isoelectric Point 3.79
Sequence EEYL

Clustering Classification

Sequence cluster S 29
Contact cluster C972
Interface cluster I933

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S29) 		Contact cluster
(C972) 		Interface cluster
(I933)
3kpl-C-A
3kpm-C-A
3kpn-C-A
3kpo-C-A
3kpp-C-A
3kpq-C-A