4J8S-B-A

PDB Title CRYSTAL STRUCTURE OF HUMAN CNOT1 MIF4G DOMAIN IN COMPLEX WITH A TTP PEPTIDE
Resolution (Å) 1.550
Classification PROTEIN BINDING

Protein

Description CCR4-NOT transcription complex subunit 1
Organism Homo sapiens
Chain A
Length 180
Binding Area (Å2) 648.77
Molecular Weight 21495.28
Aromaticity 0.14
Instability 51.01
Isoelectric Point 6.48
Sequence QQTDLSQVWPEANQHFSKEIDDEANSYFQRIYNHPPHPTMSVDEVLEMLQRFKDSTIKREREVFNCMLRNLFEEYRFFPQYPDKELHITACLFGGIIEKGLVTYMALGLALRYVLEALRKPFGSKMYYFGIAALDRFKNRLKDYPQYCQHLASISHFMQFPHHLQEYIEYGQQSRDPPVK

Peptide

Description Tristetraprolin
Organism Homo sapiens
Chain B
Length 12
Binding Area (Å2) 716.78
Hydrophobic (% a.a.)
50%
Molecular Weight 1457.72
Aromaticity 0.08
Instability 72.95
Isoelectric Point 12.30
Sequence RRLPIFNRISVS

Clustering Classification

Sequence cluster S 23
Contact cluster C1236
Interface cluster I1233

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S23) 		Contact cluster
(C1236) 		Interface cluster
(I1233)
6in9-C-B
6in9-D-A
1w0v-C-A
1w0w-C-A
4bjt-F-C
5wmo-C-A