3SP6-B-A

PDB Title STRUCTURAL BASIS FOR ILOPROST AS A DUAL PPARALPHA/DELTA AGONIST
Resolution (Å) 2.210
Classification TRANSCRIPTION

Protein

Description Peroxisome proliferator-activated receptor alpha
Organism Homo sapiens
Chain A
Length 271
Binding Area (Å2) 508.92
Molecular Weight -
Aromaticity 0.08
Instability -
Isoelectric Point 5.79
Sequence EDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMYX

Peptide

Description Peroxisome proliferator-activated receptor gamma coactivator 1-beta
Organism Homo sapiens
Chain B
Length 11
Binding Area (Å2) 589.38
Hydrophobic (% a.a.)
63%
Molecular Weight 1212.52
Aromaticity 0.00
Instability 31.01
Isoelectric Point 8.75
Sequence LSLLQKLLLAT

Clustering Classification

Sequence cluster S 173
Contact cluster C9
Interface cluster I8